反复感染鹦鹉热衣原体肺炎1例  

One case of recurrent infection with chlamydia psittaci pneumonia

作　　者：周闳远 张健 翁丹丹[2] Zhou Hongyuan;Zhang Jian;Weng Dandan(Department of Respiratory and Critical Care Medicine,Yuyao People's Hospital,Yuyao 315400,China;Department of Infectious Diseases,Yuyao People's Hospital,Yuyao 315400,China)

机构地区：[1]余姚市人民医院呼吸与危重症医学科,余姚315400 [2]余姚市人民医院感染性疾病科,余姚315400

出　　处：《中华劳动卫生职业病杂志》2025年第3期237-240,共4页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：本文对1例7个月内反复感染鹦鹉热衣原体肺炎患者的临床资料进行分析,患者有明确的活禽接触史,临床表现为干咳、稽留热、呼吸衰竭。胸部CT影像学改变表现为感染肺叶的大叶实变、磨玻璃影、支气管充气征、胸腔积液。两次感染分别通过宏基因组高通量测序(mNGS)、病原体靶向测序(tNGS)在患者支气管肺泡灌洗液中检出鹦鹉热衣原体实现了早期诊断,治疗上均以新型四环素类药物为核心,抗感染治疗后快速好转。This paper analyzed the clinical data of a patient with recurrent infection of chlamydia psittaci pneumonia within 7 months.The patient had a clear history of contact with live poultry,and the clinical manifestations were dry cough,persistent fever,and respiratory failure.Chest CT imaging changes showed lobar consolidation of infected lung lobes,ground-glass shadows,bronchial air-filling signs,and pleural effusion.The two infections were detected in bronchoalveolar lavage fluid by metagenomic next-generation sequencing(mNGS)and pathogen targeted next-generation sequencing(tNGS),respectively,to achieve early diagnosis of chlamydia psittaci pneumonia.New tetracycline drugs were used as the core of treatment for both infections,and rapid improvement was achieved after anti-infection treatment.

关 键 词：鹦鹉热 衣原体肺炎 宏基因组高通量测序 病原体靶向测序 支气管肺泡灌洗 

分 类 号：R516.7[医药卫生—内科学]