改善肺结核患者服药依从性的最佳证据总结  

Summary of the best evidence for improving medication adherence in patients with tuberculosis

作　　者：刘艺[1] 陈正英[1] 胡玲利 王小艳 LIU Yi;CHEN Zhengying;HU Lingli;WANG Xiaoyan(Jishou University,Xiangxi 416000,Hunan,China;Xiangya Affiliated Zhuzhou Hospital,Central South University,Zhuzhou 412000,Hunan,China)

机构地区：[1]吉首大学,湖南湘西416000 [2]中南大学湘雅附属株洲医院,湖南株洲412000

出　　处：《护士进修杂志》2025年第7期768-774,共7页Journal of Nurses Training

基　　金：湖南省科学技术厅项目(编号:2021SK4038)。

摘　　要：目的检索、评价和总结改善肺结核患者服药依从性的最佳证据。方法系统检索Cochrane Library、PubMed、Ebase、CINAHL、Web of Science、UpToDate、美国指南网、英国国家临床医学研究所、苏格兰校际指南网、国际指南协作网、中国知网、万方数据库、中国生物医学数据库、维普数据库等关于改善肺结核患者服药依从性的证据,包括指南、推荐实践、证据总结、专家共识、系统评价等。检索时限为建库至2023年12月31日。由2名研究者进行文献质量评价和资料提取。结果共纳入8篇文献,其中指南1篇、专家共识1篇、meta分析1篇及系统评价5篇。总结了包括卫生组织(2条证据)、社会支持(6条证据)、依从性评估(3条证据)、依从性干预(5条证据)、健康教育(5条证据)共5个方面的21条证据。结论总结的改善肺结核患者服药依从性的证据比较全面、科学,可协助临床医护人员制订改善肺结核患者服药依从性评估和干预方案,为提升肺结核患者服药依从性提供循证依据。Objective To retrieve,evaluate,and summarize the best evidence for improving medication adherence in patients with tuberculosis.Methods Systematic search of Cochrane Library,PubMed,Ebase,CINAHL,Web of Science,UpToDate,U.S.Guidelines Network,National Institute for Clinical Medicine(UK),Scottish Intercollegiate Guidelines Network(SIGN),International Guidelines Collaboration Network(IGN),China Knowledge Network(CKN),Wanfang Database(WFD),China Biomedical Database(CBD),and VIP Database(WPD)for evidence about improvement of evidence on improving medication adherence in patients with tuberculosis,including guidelines,recommended practices,evidence summaries,expert consensus,and systematic evaluations.The time frame for the search was from the establishment of the database to December 31,2023.Literature quality assessment and data extraction were performed by 2 researchers.Results A total of 8 articles were included,comprising 1 guideline,1 expert consensus,1 meta-analysis,and 5 systematic reviews.The best evidence included health organizations(2 pieces of evidence),social support(6 pieces of evidence),adherence assessment(3 pieces of evidence),adherence interventions(5 pieces of evidence),and health education(5 pieces of evidence)with a total of 21 pieces of evidence in 5 dimensions.Conclusion The evidence summarized in this study for improving medication adherence in patients with tuberculosis is relatively comprehensive and scientific,which can assist clinical healthcare professionals in developing an assessment and intervention plan for improving medication adherence in patients with tuberculosis,and provide an evidence-based basis for enhancing medication adherence in patients with tuberculosis.

关 键 词：结核 服药依从性 管理 证据总结 循证护理 

分 类 号：R473.52[医药卫生—护理学]