神经性厌食症患者再喂养综合征预防管理的最佳证据总结  

Summary of the best evidence for preventive management of refeeding syndrome in patients with anorexia nervosa

作　　者：陈梦雨 冯凤[2] 孔立[2] 韩娜[2] 刘福乐 闫兆辉 张杰 Chen Mengyu;Feng Feng;Kong Li;Han Na;Liu Fule;Yan Zhaohui;Zhang Jie(School of Nursing,Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Department of Emergency and Critical Care,Afiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250012,China;Nursing Department of Linyi Central Hospital,Linyi 276400,China)

机构地区：[1]山东中医药大学护理学院,济南250355 [2]山东中医药大学附属医院急危重症科,济南250012 [3]临沂市中心医院护理部,临沂276400

出　　处：《中国实用护理杂志》2025年第11期841-849,共9页Chinese Journal of Practical Nursing

基　　金：中国民族医药学会科研项目(2021Z1041-370104)。

摘　　要：目的系统检索、汇总神经性厌食症患者再喂养综合征预防和管理的高质量循证证据,为高危患者预防管理提供依据。方法计算机检索国内外相关数据库和专业团队网站中有关神经性厌食症患者再喂养综合征预防和管理的证据,包括临床决策、指南、专家共识、证据总结和系统评价、随机对照试验。检索时限为从建库至2024年8月。2名经过系统循证知识培训的研究者根据纳入和排除标准,独立进行文献筛查、质量评价、提取和汇总证据。结果共纳入文献15篇,其中包含指南4篇、专家共识3篇、临床决策3篇、系统评价3篇、随机对照试验2篇。从治疗团队、危险因素、风险评估、预防措施、临床诊断、处理措施以及患者安全7个方面总结出31条关于神经性厌食症患者再喂养综合征预防和管理的最佳证据。结论该研究总结的神经性厌食症再喂养综合征预防和管理的最佳证据为医护人员实施再喂养综合征预防管理措施提供了循证依据。Objective To systematically search and summarize high-quality evidence-based evidence on the prevention and management of refeeding syndrome in patients with anorexia nervosa,and to provide a basis for preventive management of patients at high risk.Methods A computerized search was conducted for evidence on the prevention and management of refeeding syndrome in patients with anorexia nervosa in relevant domestic and international databases and professional team websites,including clinical decision-making,guidelines,expert consensus,evidence summaries and systematic evaluations,and randomized controls.The search timeframe was from database construction to August 2024.Two researchers trained in systematic evidence-based knowledge independently performed literature screening,quality assessment,and extraction and summarization of evidence according to inclusion and exclusion criteria.Results A total of 15 publications were included,which contained 4 guidelines,3 expert consensus,3 clinical decision-making,3 systematic evaluations,and 2 randomized control trials.Thirty-one pieces of evidence for the prevention and management of refeeding syndrome were summarized in seven areas:treatment team,risk factors,risk assessment,preventive measures,clinical diagnosis,management measures,and patient safety.Conclusions The best evidence summarized in this study for the prevention and management of refeeding syndrome in anorexia nervosa provides an evidence-based basis for practitioners to implement refeeding syndrome prevention and management measures.

关 键 词：循证医学 神经性厌食症 再喂养综合征 再喂养 证据总结 

分 类 号：R473.74[医药卫生—护理学]