Application of Electroacupuncture Combined with Rehabilitation Training Program in Patients with Knee Osteoarthritis of Cold-dampness Obstruction Syndrome  

作　　者：Liangyun ZHOU Guohui XU Jie ZHANG Hao XU Minghui HANG Miaomiao LIU Yongjun WANG 

机构地区：[1]Huadong Hospital Affiliated to Fudan University,Shanghai 200040,China [2]School of Rehabilitation Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China [3]Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China

出　　处：《Medicinal Plant》2025年第2期62-67,70,共7页药用植物(英文)

基　　金：Supported by General Program of the National Natural Science Foundation of China(81973883);Three-Year Action Plan Project for Enhancing Clinical Skills and Clinical Innovation Capabilities of Municipal Hospitals(SHDC2020CR1010A).

摘　　要：[Objectives]To explore the effects of electroacupuncture combined with rehabilitation training on knee joint function,three-dimensional(3D)gait,and inflammatory markers in patients with knee osteoarthritis(KOA)of cold-dampness obstruction syndrome.[Methods]A total of 162 KOA patients admitted to Huadong Hospital Affiliated to Fudan University from January 2021 to May 2023 were enrolled and randomly divided into an electroacupuncture group and a control group,with 81 patients in each group.The control group received routine rehabilitation training,while the electroacupuncture group received electroacupuncture treatment in addition to the same rehabilitation training,both for 4 weeks.The efficacy,syndrome scores,Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC),Lysholm Knee Score(LKS),3D gait parameters,and levels of inflammatory markers were compared between the two groups.[Results]Following treatment,the total effective rate in the electroacupuncture group was 92.59%,which was significantly higher than 77.78%observed in the control group(P<0.05).Additionally,the electroacupuncture group exhibited lower TCM syndrome scores(P<0.05),reduced WOMAC scores,and elevated LKS scores compared to the control group(P<0.05).Gait parameters,including step frequency,step speed,stride length,initial ground contact flexion angle,maximum swing phase extension angle,and support phase extension angle,were all higher in the electroacupuncture group.Additionally,the sagittal plane maximum abduction moment was lower in the electroacupuncture group.Inflammatory markers showed that interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)were lower in the electroacupuncture group,while transforming growth factor-β1(TGF-β1)was higher(P<0.05).[Conclusions]Electroacupuncture combined with rehabilitation training effectively enhances clinical efficacy,alleviates symptoms,improves knee joint mobility and walking ability,enhances knee function scores,and reduces inflammatory levels,contributing to the rapid recovery of knee

关 键 词：Knee osteoarthritis(KOA) Cold-dampness obstruction syndrome ELECTROACUPUNCTURE Rehabilitation training Knee function scores Gait Inflammation Clinical effects Walking ability 

分 类 号：R246.9[医药卫生—针灸推拿学]