肝细胞癌组织病理学亚型的影像学特征及预后研究进展  

Research Progress on Imaging Features and Prognosis of Histopathological Subtypes of Hepatocellular Carcinoma

作　　者：司佳萌 张岚[2,3] 何旭 舒俊杰 张嘉诚 李品雄 SI Jiameng;ZHANG Lan;HE Xu;SHU Junjie;ZHANG Jiacheng;LI Pinxiong(Department of MRI,the First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China;Zhengzhou Key Laboratory of Intelligent Analysis and Utilization of Chinese Medicine Information,Henan University of Chinese Medicine,Zhengzhou 450000,China;不详)

机构地区：[1]河南中医药大学第一临床医学院,河南郑州450046 [2]河南中医药大学第一附属医院MRI科,河南郑州450000 [3]河南中医药大学中医药信息智能分析与利用郑州市重点实验室,河南郑州450000 [4]西南医科大学附属医院放射科,四川泸州646000

出　　处：《中国医学影像学杂志》2025年第3期267-273,共7页Chinese Journal of Medical Imaging

基　　金：河南省中医药科学研究专项课题(2024ZY3008);河南省医学科技攻关计划项目(LHGJ20230679);医学科学研究基金科研项目(YWJKJJHKYJJ-BXS5-22039)。

摘　　要：肝细胞癌(HCC)根据组织学表型的异质性分为增殖型HCC和非增殖型HCC,两者的临床、分子和影像学特征存在差异。这两大类包含多种病理亚型,由于其独特的分子和组织学特征,其影像学征象表现各异,且预后与典型HCC有所不同,目前临床对其治疗方案尚未明确。本文对HCC组织病理学亚型的影像学表现及其预后进行总结,为提高对HCC各病理亚型的认知和判断、选择和优化治疗策略提供理论依据。Hepatocellular carcinoma(HCC)is categorized into two major classes based on the heterogeneity of histological phenotypes:proliferative HCC and non-proliferative HCC.These classes exhibit distinct clinical,molecular and imaging characteristics.Within these two major categories,there exist multiple pathological subtypes,each demonstrating unique molecular and histological features that manifest differently in imaging findings.Additionally,the prognosis of these HCC pathological subtypes diverges from that of not-otherwise-specified HCC,and current clinical guidelines for their treatment remain unclear.This article aims to summarize the imaging manifestations and prognosis of the histopathological subtypes of HCC,so as to enhance identification and judgement of HCC subtypes,and to provide a theoretical basis for selecting appropriate therapeutic strategies.

关 键 词：癌 肝细胞 磁共振成像 病理学 增殖型 非增殖型 预后 综述 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.7[医药卫生—诊断学]