MRI影像学特征预测肝细胞癌预后研究进展  

Research Progress on Prognosis Prediction of Hepatocellular Carcinoma Based on MRI Features

作　　者：严艺豪 张岚[1,3] 许倩 司佳萌 时付坤 舒俊杰 张嘉诚 何旭 YAN Yihao;ZHANG Lan;XU Qian;SI Jiameng;SHI Fukun;SHU Junjie;ZHANG Jiacheng;HE Xu(Department of MRI,the First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China;Zhengzhou Key Laboratory of Intelligent Analysis and Utilization of Chinese Medicine Information,Henan University of Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第一附属医院MRI科,河南郑州450000 [2]河南中医药大学第一临床医学院,河南郑州450046 [3]河南中医药大学中医药信息智能分析与利用郑州市重点实验室,河南郑州450000

出　　处：《中国医学影像学杂志》2025年第3期274-279,共6页Chinese Journal of Medical Imaging

基　　金：国家自然科学基金(82402217);河南省中医药科学研究专项课题(2024ZY3008);医学科学研究基金科研项目(YWJKJJHKYJJ-BXS5-22039)。

摘　　要：在临床实践中,肝细胞癌诊断主要基于影像学,影像学特征不典型的病例需辅以病理学分析。随着精准医学理念的深化,关注点已从单纯诊断向疗效预测评价延伸,基于影像特征的预后生物标志物成为目前肝细胞癌研究热点。近年研究表明,影像学征象不仅能反映肿瘤异质性,还能提供肝细胞癌相关的预后信息,有助于无创性预测预后,为优化治疗决策提供客观依据。本综述全面概述与肝细胞癌预后相关的MRI影像学特征,旨在指导个性化治疗,改善肝细胞癌患者的生存结局。In clinical practice,the diagnosis of hepatocellular carcinoma primarily relies on imaging findings.For cases with atypical imaging features or insufficient diagnostic specificity,pathological analysis remains essential.With the advancement of precision medicine,research focus has expanded from pure diagnostic evaluation to therapeutic efficacy prediction.Imaging-based prognostic biomarkers have emerged as a key research frontier in hepatocellular carcinoma management.Although accurate diagnosis remains paramount,current investigations increasingly prioritize the identification of biomarkers for treatment response prediction and outcome stratification.Recent studies demonstrate that radiological characteristics not only reflect tumor heterogeneity but also carry prognostic implications for hepatocellular carcinoma.These imaging biomarkers enable non-invasive outcome prediction and provide objective evidence to optimize therapeutic decision-making.This comprehensive review summarizes MRI-derived imaging features associated with hepatocellular carcinoma prognosis,aiming to guide personalized treatment strategies and ultimately improve survival outcomes for hepatocellular carcinoma patients.

关 键 词：癌 肝细胞 磁共振成像 病理亚型 预后 综述 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.7[医药卫生—诊断学]