Biomimetic two-stage micro@nanomotor with weak acid-triggered release of nanomotors  

作　　者：Liang Gui Jiameng Feng Haodong Guo Xiaoyu Li Junjie Zou Xin Du 

机构地区：[1]Department of Vascular Surgery,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China [2]Beijing Key Laboratory for Bioengineering and Sensing Technology,School of Chemistry and Biological Engineering,University of Science and Technology Beijing,Beijing 100083,China [3]National Engineering Research Center of green recycling for strategic metal resources,Key Laboratory of Green Process and Engineering,Institutional Center for Shared Technologies and Facilities,Institute of Process Engineering,Chinese Academic of Sciences,University of Chinese Academic of Sciences,Beijing 100190,China

出　　处：《Nano Research》2025年第4期247-254,共8页纳米研究(英文版)

基　　金：supported by Fundamental Research Funds for the Central Universities(No.FRF-BR-23-02B);China Postdoctoral Science Foundation(No.2023M731408);Jiangsu Funding Program for Excellent Postdoctoral Talent(No.2023ZB640);Jiangsu Province Capability Improvement Project through Science,technology and Education(Jiangsu Provincial Medical Key Discipline,ZDXK202222);Natural Science Foundation of Jiangsu Province(No.BK20230731).

摘　　要：Bionic micro/nanomotor systems,which combine biomimetic design with the motion performance,have shown great potential in many fields.However,so far,it remains a challenge to design and fabricate biomimetic micro/nanomotors with high flexibility to perform complex tasks in complicated and changeable environments.In this work,inspired by the suckerfishes(guest)-shark(host)motion behavior,we designed and prepared a kind of intelligent two-stage micro@nanomotor with weak acid-triggered release of nanomotor.When the suckerfishes,who clinged to the surface of large fish or the bottom of boat and marched with them,reached bait-rich waters,they detached from the host to engage in foraging behavior.Inspired by the suckerfishes-shark system and the coordinated bond interaction,a large amount of Janus Au-Pt nanomotors with hydrogen peroxide(H_(2)O_(2))-driven capacity,analogous to suckerfishes,were attached onto immovable yolk-shell structured polydopamine-mesoporous silica(PDA-MS)micromotor as the host to create two-stage PDA-MS@Au-Pt [e-mail]-MS@Au-Pt micro@nanomotor moved directionally by self-thermophoresis under the propulsion of near infrared ray(NIR)light with low power density.When the PDA-MS@Au-Pt entered into the weak acidic environment formed by a low concentration of H_(2)O_(2),most small Au-Pt nanomotors were detached from the surface of PDA-MS due to the weak acidic sensitivity of the coordinated bond,and then performed self-diffusiophoresis in the environment containing a low concentration of H_(2)O_(2) as a chemical fuel.This bionic intelligent system,which consists of a large-sized micromotor and lots of small-sized nanomotors,should provide a new insight for active two-stage cargo delivery.

关 键 词：micro/nanomotor bionic design acid-triggered release H_(2)O_(2)propulsion near infrared ray(NIR)light propulsion 

分 类 号：TB383[一般工业技术—材料科学与工程]