机构地区:[1]郑州市第二人民医院疾病预防控制科,河南郑州450000
出 处:《现代疾病预防控制》2025年第3期219-222,共4页MODERN DISEASE CONTROL AND PREVENTION
摘 要:目的通过对患者术前传染病4项检测结果分析,探讨患者乙型肝炎病毒、丙型肝炎病毒、人类免疫缺陷病毒及梅毒螺旋体感染状况及临床意义。方法选取2019—2021年于郑州市第二人民医院住院行手术治疗的39568例患者为研究对象,采用酶联免疫法检测患者术前乙肝表面抗原(HBsAg)、丙肝抗体(抗-HCV)、人类免疫缺陷病毒抗体(抗-HIV)和梅毒螺旋体抗体(抗-TP),分析各指标阳性结果在不同年份、性别、年龄段、科室的分布及多重感染情况。结果39568例患者传染病4项总阳性率为4.61%,HBsAg、抗-HCV、抗-HIV和抗-TP的阳性率分别为3.06%、0.78%、0.05%、0.82%;不同年份传染病4项总阳性率差异无统计学意义(χ^(2)=2.230,P>0.05);男性患者HBsAg、抗-HIV阳性率高于女性患者(3.32%vs 2.83%,0.08%vs 0.01%),而抗-HCV阳性率低于女性患者(0.64%vs 0.90%),差异均有统计学意义(χ^(2)=8.063、10.192、8.393,P均<0.05);<18、18~<45、45~<60、60~<75、≥75岁年龄组患者传染病4项总阳性率分别为0.20%、5.23%、6.83%、5.66%和4.59%,眼科、内科、外科、妇产科、儿科的患者传染病4项总阳性率分别为5.71%、5.12%、4.07%、6.11%和1.01%,不同年龄段、不同科室传染病4项总阳性率、HBsAg、抗-HCV和抗-TP阳性率差异均有统计学意义(P均<0.05)。34例患者共发生6种模式多重感染,多重感染占1.86%(34/1826),其中HBsAg和抗-TP合并感染最多(32.35%,11/34)。结论术前传染病4项检测有助于明确患者健康状况,有效预防医院感染,保护医患双方身体健康。Objective To explore the infection status and clinical significance of hepatitis B virus,hepatitis C virus,human immunodeficiency virus and treponema pallidum by analyzing the results of the four infectious disease tests in the inpatients before surgery.Methods A total of 39568 inpatients who underwent surgery in Zhengzhou Second Hospital from 2019 to 2021 were selected as study subjects.Enzyme-linked immunoassay was used to detect hepatitis B surface antigen(HBsAg),hepatitis C antibody(anti-HCV),human immunodeficiency virus antibody(anti-HIV)and treponema pallidum antibody(anti-TP)in the preoperative inpatients.The distribution of positive results of each index across different years,sex,age groups,departments and multiple infections were analyzed.Results The overall positive rate for the four infectious diseases among the 39568 patients was 4.61%,and the positive rates were 3.06%,0.78%,0.05%,and 0.82%for HBsAg,anti-HCV,anti-HIV,and anti-TP,respectively.There was no significant difference in the overall positive rate of the four infectious diseases across different years(χ^(2)=2.230,P>0.05).The positive rates of HBsAg and anti-HIV in male patients were higher than those in female patients(3.32%vs 2.83%;0.08%vs 0.01%),while the positive rate of anti-HCV was lower in male patients than that in female patients(0.64%vs 0.90%).The differences were statistically significant(χ^(2)=8.063,10.192,8.393,respectively;all P<0.05).The overall positive rates of the four infectious diseases in<18,18~<45,45~<60,60~<75 and≥75 age groups were 0.20%,5.23%,6.83%,5.66%and 4.59%,respectively.The overall positive rates of the four infectious diseases in ophthalmology department,internal medicine department,surgery department,obstetrics and gynecology department and pediatrics department were 5.71%,5.12%,4.07%,6.11%and 1.01%,respectively.There were significant differences in the overall positive rates of the four infectious diseases,in the positive rates of HBsAg,anti-HCV and anti-TP across different age groups and departments(All P
关 键 词:乙肝表面抗原 丙肝抗体 人类免疫缺陷病毒抗体 梅毒螺旋体抗体
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