祛白消斑汤加减联合NB-UVB治疗稳定期白癜风临床疗效分析  

Clinical Efficacy of Modified Qubai Xiaoban Decoction Combined with NB-UVB on Stable Vitiligo

作　　者：韩宏彬 韩莉[2] 王展[3] 王清 江丽华 HAN Hongbin;HAN Li;WANG Zhan;WANG Qing;JIANG Lihua(Department of Traditional Chinese Medicine,the Second People's Hospital of Hengshui,Hengshui 053000,Hebei,China;Department of Dermatology,the Second People's Hospital of Hengshui,Hengshui 053000,Hebei,China;Department of Laboratory Medicine,the Second People's Hospital of Hengshui,Hengshui 053000,Hebei,China;Department of Glandular Surgery,the Second People's Hospital of Hengshui,Hengshui 053000,Hebei,China;Injection Room,the Second People's Hospital of Hengshui,Hengshui 053000,Hebei,China)

机构地区：[1]衡水市第二人民医院中医科,河北衡水053000 [2]衡水市第二人民医院皮肤科,河北衡水053000 [3]衡水市第二人民医院检验科,河北衡水053000 [4]衡水市第二人民医院腺体外科,河北衡水053000 [5]衡水市第二人民医院注射室,河北衡水053000

出　　处：《中国美容医学》2025年第4期86-90,共5页Chinese Journal of Aesthetic Medicine

基　　金：衡水市科学技术研究与发展计划项目(编号:2022014090Z)。

摘　　要：目的:探究祛白消斑汤加减联合窄谱中波紫外线(NB-UVB)治疗稳定期白癜风疗效及对皮损色素恢复效果的影响。方法:遴选衡水市第二人民医院皮肤科2022年1月-2023年12月收治的90例稳定期白癜风患者,将患者随机分为两组,光疗组接受NB-UVB治疗,消斑汤组在NB-UVB治疗基础上加用祛白消斑汤。结果:消斑汤组总有效率显著高于光疗组(P<0.05);治疗后,两组色素积分显著上升,皮损面积、VASI评分显著下降(P<0.05),消斑汤组各项指标优于光疗组(P<0.05)。结论:祛白消斑汤加减联合NB-UVB可有效治疗白癜风,降低患者皮损面积,改善氧化应激指标,不良反应小,满意度高,值得应用。Objective To explore the efficacy of modified Qubai Xiaoban decoction combined with narrow-band ultraviolet B(NB-UVB)in the treatment of stable vitiligo and its influence on the pigment recovery effect of skin lesions.Methods 90 patients with stable vitiligo in department of dermatology of the Second People’s Hospital of Hengshui were selected from January 2022 to December 2023,and were randomly divided into two groups.The phototherapy group received NB-UVB treatment,whereas Xiaoban decoction group was added with modified Qubai Xiaoban decoction based on NB-UVB treatment.Results The total effective rate in Xiaoban decoction group was significantly higher than that in phototherapy group(P<0.05).After treatment,the pigment score in both groups was increased significantly while the skin lesion area and VASI were decreased significantly(P<0.05),and the indicators in Xiaoban decoction group were better than those in phototherapy group(P<0.05).Conclusion Modified Qubai Xiaoban decoction combined with NB-UVB can effectively treat vitiligo,reduce the skin lesion area,and improve the oxidative stress indicators,with few adverse reactions and high satisfaction.

关 键 词：白癜风 祛白消斑汤 窄谱中波紫外线 皮肤美容 氧化应激 色素沉着 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]