宫内发育迟缓脂质代谢异常的研究进展  

Research progress on abnormal lipid metabolism in intrauterine growth retardation

作　　者：王思宇 申莲花 袁冰舒(综述) 李丽娟(审校) WANG Siyu;SHEN Lianhua;YUAN Bingshu;LI Lijuan(Department of Pathophsiology,Zunyi Medical University,Zunyi 563000,Guizhou,China)

机构地区：[1]遵义医科大学病理生理学教研室,遵义563000

出　　处：《医学研究与战创伤救治》2025年第3期315-320,共6页Journal of Medical Research & Combat Trauma Care

基　　金：国家自然科学基金(32160221);贵州省科技计划项目(黔科合基础-ZK[2022]一般603)。

摘　　要：宫内发育迟缓(IUGR)是由于孕期营养不良或胎盘功能不全等造成个体出现生长发育受损及低出生体重的现象。IUGR个体常伴随脂质代谢改变,是其成年后易发生肥胖、高脂血症等代谢性疾病的重要根源。文章主要从三酰甘油、脂肪酸和胆固醇的代谢及转运异常等方面对IUGR个体的脂质代谢改变及其发生机制进行综述。Intrauterine Growth Restriction(IUGR)is a condition characterized by impaired growth and low birth weight due to factors like poor nutrition or placental insufficiency during pregnancy.IUGR individuals are often accompanied by abnormal lipid me-tabolism,which is a significant contributor to metabolic disorders such as obesity and hyperlipidemia in adulthood.This review summa-rized the changes of lipid metabolism in IUGR individuals,focusing on abnormalities in the metabolism and transport of triglycerides,fatty acids,and cholesterol,along with their underlying mechanisms.

关 键 词：宫内发育迟缓 脂质代谢异常 代谢综合征 

分 类 号：R714[医药卫生—妇产科学]