驻马店市中心医院综合ICU多重耐药鲍曼不动杆菌感染的影响因素  

Influencing Factors of Multidrug-Resistant Acinetobacter Baumannii Infection in the Comprehensive ICU of Zhumadian Central Hospital

作　　者：黄晶 李佳慧 张爱荣 娄峻 HUANG Jing;LI Jiahui;ZHANG Airong;LOU Jun(Department of Clinical Laboratory,Zhumadian Central Hospital,Zhumadian 463000,China;Henan Medical School,Kaifeng 475004,China)

机构地区：[1]驻马店市中心医院医学检验科,河南驻马店463000 [2]河南大学医学院,河南开封475004

出　　处：《河南医学研究》2025年第7期1219-1223,共5页Henan Medical Research

摘　　要：目的探讨驻马店市中心医院综合重症加强护理病房(ICU)多重耐药鲍曼不动杆菌(MDRAB)感染的影响因素。方法回顾性收集驻马店市中心医院2021年1月至2024年1月综合ICU 216例鲍曼不动杆菌(AB)感染中老年患者的临床资料,依据AB患者感染多重耐药情况分为MDRAB感染组(85例)和非MDRAB感染组(131例),收集患者入住综合ICU时基线资料及AB感染前3 d实验室指标,采用logistic回归分析驻马店市中心医院综合ICU患者MDRAB感染的影响因素。结果MDRAB感染组年龄、气管插管占比、AB感染前使用抗菌药物种类、慢性阻塞性肺疾病占比均高于非MDRAB感染组,血红蛋白水平、白蛋白水平、白细胞计数水平低于非MDRAB感染组,差异有统计学意义(P<0.05);经logistic回归分析,年龄越大、AB感染前使用抗菌药物种类越多、合并慢性阻塞性肺疾病、血红蛋白水平低、白蛋白水平低、白细胞计数水平低是驻马店市中心医院综合ICU患者MDRAB感染的危险因素(OR>1,P<0.05)。结论年龄越大、AB感染前使用抗菌药物种类越多、合并慢性阻塞性肺疾病、血红蛋白水平低、白蛋白水平低、白细胞计数水平低是驻马店市中心医院综合ICU患者MDRAB感染的重点人群,且上述指标均是医院综合ICU患者MDRAB感染的影响因素。Objective To explore the influencing factors of multidrug-resistant Acinetobacter baumannii(MDRAB)infection in the comprehensive intensive care unit(ICU)of Zhumadian Central Hospital.Methods A retrospective collection of clinical data was conducted on 216 middle-aged and elderly patients with Acinetobacter baumannii(AB)infection in the comprehensive ICU of Zhumadian Central Hospital from January 2021 to January 2024.Based on the multidrug-resistant status of AB patients,they were divided into MDRAB infection group(85 cases)and non MDRAB infection group(131 cases).Baseline data and laboratory indicators 3 days before AB infection were collected at the time of admission to the comprehensive ICU.Logistic regression analysis was used to identify the influencing factors of MDRAB infection in patients in the comprehensive ICU of Zhumadian Central Hospital.Results The age,proportion of tracheal intubation,types of antibiotics used before AB infection,and proportion of chronic obstructive pulmonary disease(COPD)in the MDRAB infection group were all higher than those in the non MDRAB infection group.The levels of hemoglobin,albumin,and white blood cell count were lower than those in the non MDRAB infection group,with statistical significant differences(P<0.05).According to logistic regression analysis,older age,more types of antibiotics used before AB infection,concomitant chronic obstructive pulmonary disease,low hemoglobin levels,low albumin levels,and low white blood cell count levels were risk factors for MDRAB infection in patients in the comprehensive ICU of Zhumadian Central Hospital(OR>1,P<0.05).Conclusion The older the age,the more types of antibiotics used before AB infection,the presence of chronic obstructive pulmonary disease,low hemoglobin levels,low albumin levels,and low white blood cell count levels are the key populations for MDRAB infection in the comprehensive ICU of Zhumadian Central Hospital,and the above indicators are all influencing factors for MDRAB infection in hospital comprehensive ICU patient

关 键 词：综合重症加强护理病房 多重耐药 鲍曼不动杆菌 病原学 影响因素 

分 类 号：R446.5[医药卫生—诊断学]