化疗致外周神经毒性非药物管理的最佳证据总结  

Summary of the best evidence for nonpharmacological management of chemotherapy-induced peripheral neuropathy

作　　者：付练 吴文碧 丁彩艳[3] 郑素华[4] 孙志琴[1] 薛佳韵 Fu Lian;Wu Wenbi;Ding Caiyan;Zheng Suhua;Sun Zhiqin;Xue Jiayun(Department of Education,the Third Affiliated Hospital of Nanjing Medical University,Changzhou 213000,China;Nursing School,Pingxiang Health Vocational College,Pingxiang 337000,China;Nursing Teaching and Research Room,the Third Affiliated Hospital of Nanjing Medical University,Changzhou 213000,China;Cancer Department,the Third Affliated Hospital of Nanjing Medical University,Changzhou 213000,China;School of Nursing,Nanjing Medical University,Nanjing 210000,China)

机构地区：[1]南京医科大学第三附属医院教育教学科,常州213000 [2]萍乡卫生职业学院护理学院,萍乡337000 [3]南京医科大学第三附属医院护理教研室,常州213000 [4]南京医科大学第三附属医院肿瘤科,常州213000 [5]南京医科大学护理学院,南京210000

出　　处：《中华现代护理杂志》2025年第12期1627-1635,共9页Chinese Journal of Modern Nursing

基　　金：常州市科技计划资助应用基础研究面上项目(CJ20230074);常州大学一常州市第二人民医院护理专项科研课题(CDHL202405)。

摘　　要：目的检索、评价并汇总化疗所致外周神经毒性(CIPN)非药物管理的相关证据,为癌症化疗患者的临床护理提供循证依据。方法去按照循证检索资源的“6S”模型,系统检索国内外网站或数据库中关于CIPN非药物管理的所有证据,包括指南、证据总结、临床决策、专家共识、系统评价。检索时限为2019年1月1日-2023年12月31日。结果共纳入19篇文献,其中证据总结1篇、指南1篇、专家共识6篇、系统评价11篇。主要汇总了评估/筛查、预防、干预、临床管理、健康教育5个方面的40条最佳证据。结论本研究总结的40条CIPN非药物管理的最佳证据可用于预防或减轻癌症患者CIPN症状,临床医护人员应根据不同临床情境,结合患者自身条件及证据实施的可行性、适宜性,酌情选择证据条目。Objective To retrieve,evaluate,and summarize evidence on the nonpharmacological management of chemotherapy-induced peripheral neuropathy(CIPN)to provide an evidence-based basis for the clinical nursing of patients undergoing cancer chemotherapy.Methods sIn accordance with the"6S"model of evidence-based search resources,guidelines,evidence summaries,clinical decisions,expert consensus,and systematic reviews on the nonpharmacological management of CIPN were systematically searched on domestic and international websites or databases.The search period was from January 1,2019 to December 31,2023.Results A total of 19 papers were included,including one evidence summary,one guideline,six expert consensus,and 1l systematic reviews.Forty pieces of best evidence in five aspects of assessment/screening,prevention,intervention,clinical management,and health education were summarized.Conclusions The 40 best evidence for nonpharmacological management of CIPN summarized can be used to prevent or reduce CIPN in cancer patients.Clinical medical and nursing staff should select evidence entries as appropriate for different clinical situations,taking into account the patient's own condition and the feasibility and appropriateness of evidence implementation.

关 键 词：肿瘤 化疗致外周神经毒性 非药物管理 循证护理 证据总结 

分 类 号：R473.73[医药卫生—护理学]