疫苗偏好驱动不同群体预防接种决策:基于选择性试验的系统综述  

Vaccine preferences driving vaccine decision making of different target groups: a systematic review of choice-based experiment

作　　者：罗小福[1] 张超 韩利萍 沈建勇[2] 胡昱[3] 丁林玲 吕华坤[3] Luo Xiaofu;Zhang Chao;Han Liping;Shen Jianyong;Hu Yu;Ding Linling;Lyu Huakun(Department of Immunology,Huzhou Center for Disease Prevention and Control,Huzhou 313000,China;Administration Office,Huzhou Center for Disease Prevention and Control,Huzhou 313000,China;Department of Immunology,Zhejiang Province Center for Disease Prevention and Control,Hangzhou 310000,China)

机构地区：[1]湖州市疾病预防控制中心免疫规划科,湖州313000 [2]湖州市疾病预防控制中心行政办公室,湖州313000 [3]浙江省疾病预防控制中心免疫所,杭州310000

出　　处：《国际流行病学传染病学杂志》2025年第1期47-54,共8页International Journal of Epidemiology and Infectious Disease

基　　金：湖州市疾病预防控制中心科技计划(KJJH202208)。

摘　　要：目的:对国内外疫苗偏好领域选择性试验研究进行系统检索,描述分析影响受种者或其监护人对疫苗或预防接种偏好的属性。方法:共检索国内外5个数据库中所有使用选择性试验评价疫苗、预防接种项目偏好的文献,提取纳入文献中基本信息、研究设计、研究方法、数据分析、实施过程和研究结果等。使用统一量表进行文献质量评价,疫苗属性划分为结果、过程、费用和其他共4类。描述分析各类疫苗属性在不同人群中的重要性,频数统计不同人群疫苗偏好的各类疫苗属性、以及对预防接种偏好有显著影响的疫苗属性。结果:本次系统综述纳入文献特征分析共42篇,其中高质量文献16篇。研究对象集中在监护人(47.62%,20/42)和受种者(35.71%,15/42)。保护持久性、疫苗效果、疫苗接种风险等结局类属性,全程接种所需剂次数、疫苗可及性等过程类属性,费用类属性,接种建议等其他类属性对受种者疫苗偏好影响较大;疫苗效果、疫苗接种风险等结局类属性,目标人群、接种所需时间等过程类属性、费用类属性、疾病风险、疫苗信息等其他类属性对监护人的疫苗偏好影响较大。结论:在受种者、监护人中,疫苗偏好的属性相似,可开展疫苗安全性、疫苗保护效果、保护持久性、疫苗可预防疾病等方面的宣传来促进公众形成积极的疫苗接种行为。Objective:To systematically review choice-based experiments on vaccine preferences conducted both domestically and internationally,and analyze the attributes that influence the vaccine or vaccination preferences of recipients or their guardians.Methods:A comprehensive search was conducted in five databases,identifying all literature that used choice-based experiments to assess vaccine and vaccination preference.Basic information,research design,methods,data analysis,implementation processes,and results were extracted from the included studies.A standardized scale was used for quality assessment.Vaccine attributes were categorized into four types:outcomes,processes,costs,and others.Descriptive analysis was performed to identify the importance of each vaccine attribute across different populations,with frequency statistics used to examine vaccine preferences within different groups.Additionally,vaccine attributes that significantly impacted vaccination preferences were analyzed.Results:A total of 42 studies were included in the systematic review,with 16 high-quality studies.The subjects primarily consisted of guardians(47.62%,20/42)and vaccine recipients(35.71%,15/42).Outcome-related attributes such as protection duration,vaccine efficacy,and risk of vaccination,process-related attributes such as doses required for full vaccination and vaccine accessibility,cost-related attributes,and other attributes like vaccination recommendations had a significant influence on vaccine preferences of recipients.For guardians,outcome-related attributes such as vaccine efficacy and vaccination risk,process-related attributes such as target population and time required for vaccination,cost-related attributes,and other attributes such as disease risk and vaccine information were of greater importance in shaping vaccine preferences.Conclusions:Vaccine preferences among recipients and guardians show similar significant attributes.Public health campaigns should focus on promoting vaccine safety,protective effectiveness,longevity of pro

关 键 词：疫苗 预防接种 偏好 影响因素 选择性试验 

分 类 号：R186[医药卫生—流行病学]