164例血管性抑郁患者的中医证素特征研究  

A study of the characteristics of Traditional Chinese Medicine pattern factors in 164 patients with vascular depression

作　　者：杨丽旋 敖与天 代宝安 李景淳 董凯强 李彦楠 郭蓉娟 YANG Lixuan;AO Yutian;DAI Bao′an;LI Jingchun;DONG Kaiqiang;LI Yannan;GUO Rongjuan(Beijing University of Chinese Medicine,Beijing 100029;Beijing Fengtai District Hospital of Traditional Chinese Medicine;Dongfang Hospital,Beijing University of Chinese Medicine)

机构地区：[1]北京中医药大学,北京100029 [2]北京市丰台区中医医院 [3]北京中医药大学东方医院

出　　处：《现代中医临床》2025年第2期24-30,共7页Modern Chinese Clinical Medicine

基　　金：国家自然科学基金重点支持项目(No.U21A20401);国家自然科学基金项目(No.81874422);北京中医药大学重点攻关项目(No.2020-JYB-ZDGG-121)。

摘　　要：目的 探讨血管性抑郁患者中医证素特征。方法 收集164例血管性抑郁患者的一般资料及中医四诊信息,通过对患者中医症状、体征所归属的证素分别进行加权求和,以分析其证素分布特征。结果 在纳入的164例患者中,肝(81.71%)、心神(43.90%)、肾(29.27%)、脾(27.44%)为主要病位证素,气滞(75.61%)、阴虚(74.39%)、气虚(72.56%)、阳虚(61.59%)、血虚(57.32%)为主要病性证素。病位证素脾、胃、肺在不同抑郁程度中的构成比差异具有统计学意义(P<0.05),病性证素气虚、血虚在不同抑郁程度中的构成比差异具有统计学意义(P<0.05)。结论 通过对病位病性证素总结发现,本病多应于肝,易乘脾,损肾精,耗心神,以气滞贯穿始终,随着病情发展,以气虚为重,兼见血虚、阴虚及阳虚。Objective To explore the characteristics of Traditional Chinese Medicine(TCM)pattern factors in patients with vascular depression.Methods The general data and information of 164 patients with vascular depression and the TCM four diagnoses were collected,and the distribution characteristics of the pattern factors were analyzed by weighting and summing the evidence elements attributed to the patients'TCM symptoms and signs,respectively.Results Among the 164 patients included,liver(81.71%),heart and spirit(43.90%),kidney(29.27%),and spleen(27.44%)were the main disease location pattern factors,and qi stagnation(75.61%),yin deficiency(74.39%),qi deficiency(72.56%),yang deficiency(61.59%),and blood deficiency(57.32%)were the main disease nature pattern factors.The composition ratios of the location factors of the spleen,stomach and lung in different degrees of depression were statistically different(P<0.05),and the composition ratios of the nature factors of qi deficiency and blood deficiency in different degrees of depression were statistically different(P<0.05).Conclusion By summarizing the symptoms of the disease,it is found that the disease is mostly due to the liver,easily attacks the spleen,damages the kidney essence and depletes the heart and spirit,with qi stagnation running through the whole process.As the disease progresses,qi deficiency is the most important factor,and blood,yin and yang deficiencies are seen at the same time.

关 键 词：血管性抑郁 中医证素 分布特征 

分 类 号：R2-03[医药卫生—中医学] R277.7