体外反搏技术在冠心病患者心脏康复中治疗效果的Meta分析  

Therapeutic effect of external counterpulsation on cardiac rehabilitation in patients with coronary heart disease-a meta-analysis

作　　者：王伟韬 刘铁军[3] 刘自双 胡喜莲 杨澄 孙拉娣 WANG Wei-tao;LIU Tie-jun;LIU Zi-shuang;HU Xi-lian;YANG Cheng;SUN La-di(Rehabilitation Management Center,Affiliated Beijing Rehabilitation Hospital of Capital Medical University,Beijing,100144,China)

机构地区：[1]首都医科大学附属北京康复医院康复诊疗中心,北京市100144 [2]首都医科大学附属北京康复医院老年康复中心,北京市100144 [3]首都医科大学附属北京康复医院泌尿与代谢康复中心,北京市100144 [4]北京朝阳中西医结合急诊抢救医院

出　　处：《心血管康复医学杂志》2025年第2期172-179,共8页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：首都卫生发展科研专项基金(2024-2-2251)。

摘　　要：目的:基于Meta分析评价体外反搏技术对冠心病患者的临床康复效果。方法:计算机检索中国知网、万方数据知识服务平台、维普网、中国生物医学文献数据库、PubMed、Web of Science、Cochrane Library、Embase等数据库从建库至2024年5月关于体外反搏技术对冠心病患者康复效果的随机对照试验(RCTs)和前瞻性队列研究。采用随机效应(P<0.5或I 2≥50%)或固定效应模型(其他情况)计算总效应量和95%置信区间。结果:最终纳入13篇文献。与对照组相比,干预组的左心室射血分数(MD=4.15,95%CI 2.55~5.76,P<0.001)、每搏输出量(MD=9.11,95%CI 7.59~10.64,P<0.001)、峰值摄氧量(MD=5.42,95%CI 2.53~8.32,P<0.001)、6min步行距离(MD=31.14,95%CI 24.89~37.40,P<0.001)、代谢当量(MD=0.58,95%CI 0.45~0.71,P<0.001)、运动持续时间(SMD=0.77,95%CI 0.55~0.99,P<0.001)、氧脉搏(MD=0.88,95%CI 0.68~1.09,P<0.001)显著升高;左心室舒张末期内径显著减小(MD=-3.91,95%CI-5.20~-2.61,P<0.001)。结论:体外反搏技术能有效提升冠心病患者的心功能、提升运动能力及活动耐量。Objective:To evaluate the clinical rehabilitation effect of external counterpulsation(ECP)on patients with coronary heart disease(CHD)by meta-analysis.Methods:We searched the databases of CNKI,WanFang,VIP,CBM,PubMed,Web of Science,Cochrane Library and Embase for randomized controlled trials(RCTs)and prospective cohort studies upon rehabilitative effect of ECP on CHD patients before May 2024.And meta-analysis was conducted to calculate the pooled MD and 95%CI using the random(P<0.5 or I 2≥50%)or fixed effect models(other situations).Results:13 eligible literatures were finally included in the meta-analysis.Compared with participants in control group,those in trial group had significant higher left ventricular ejection fraction(MD=4.15,95%CI 2.55~5.76,P<0.001),stroke volume(MD=9.11,95%CI 7.59~10.64,P<0.001),peak oxygen uptake(MD=5.42,95%CI 2.53~8.32,P<0.001),6-min walking distance(MD=31.14,95%CI 24.89~37.40,P<0.001),metabolic equivalent(MD=0.58,95%CI 0.45~0.71,P<0.001),exercise duration time(SMD=0.77,95%CI 0.55~0.99,P<0.001),oxygen pulse(MD=0.88,95%CI 0.68~1.09,P<0.001),and significant lower left ventricular end-diastolic diameter(MD=-3.19,95%CI-5.20~-2.61,P<0.001).Conclusion:This study showed that ECP could effectively improve heart function,exercise capacity and tolerance of CHD patients.

关 键 词：冠心病 反搏动术 META分析 

分 类 号：R541.4[医药卫生—心血管疾病]