Optofluidic paper-based analytical device for discriminative detection of organic substances via digital color coding  

作　　者：Jinsol Choi Chi Yeung Oh Gong Qian Tae Soup Shim Heon-Ho Jeong 

机构地区：[1]Department of Chemical and Biomolecular Engineering,Chonnam National University,50 Daehak-ro,Yeosu-si,Jeollanam-do 59626,Republic of Korea [2]Department of Energy Systems Research,Ajou University,206 World cup-ro,Suwon-si,Gyeonggi-do 16499,Republic of Korea [3]Department of Chemical Engineering,Ajou University,206 World cup-ro,Suwon-si,Gyeonggi-do 16499,Republic of Korea

出　　处：《Microsystems & Nanoengineering》2025年第1期186-195,共10页微系统与纳米工程(英文)

基　　金：supported by the National Research Foundation of Korea(NRF)Grant funded by the Korea Government(NRF-2020R1C1C1005505 and NRF-2022R1F1A106519512).

摘　　要：Developing a portable yet affordable method for the discrimination of chemical substances with good sensitivity and selectivity is essential for on-site visual detection of unknown substances.Herein,we propose an optofluidic paper-based analytical device(PAD)that consists of a macromolecule-driven flow(MDF)gate and photonic crystal(PhC)coding units,enabling portable and scalable detection and discrimination of various organic chemical,mimicking the olfactory system.The MDF gate is designed for precise flow control of liquid analytes,which depends on intermolecular interactions between the polymer at the MDF gate and the liquid analytes.Subsequently,the PhC coding unit allows for visualizing the result obtained from the MDF gate and generating differential optical patterns.We fabricate an optofluidic PAD by integrating two coding units into a three-dimensional(3D)microfluidic paper within a 3D-printed cartridge.The optofluidic PADs clearly distinguish 11 organic chemicals with digital readout of pattern recognition from colorimetric signals.We believe that our optofluidic coding strategy mimicking the olfactory system opens up a wide range of potential applications in colorimetric monitoring of chemicals observed in environment.

关 键 词：organic chemicalmimicking olfactory systemthe photonic crystal coding precise flow co chemical substances optofluidic paper based analytical device macromolecule driven flow gate portable detection 

分 类 号：O65[理学—分析化学]