深圳市宝安区2006—2023年恙虫病流行特征  

Epidemic characteristics of tsutsugamushi disease in Bao'an District,Shenzhen from 2006 to 2023

作　　者：罗剑锋 曾权威 陈亿雄[3] 黄振宇[3] 李苑[3] LUO Jianfeng;ZENG Quanwei;CHEN Yixiong;HUANG Zhenyu;LI Yuan(Shiyan People's Hospital of Bao'an District,Shenzhen,Guangdong 518108,China;Shenzhen Integrated Traditional Chinese and Western Medicine Hospital,Shenzhen,Guangdong 518104,China;Bao'an District Center for Disease Control and Prevention,Shenzhen,Guangdong 518101,China)

机构地区：[1]深圳市宝安区石岩人民医院,广东深圳518108 [2]深圳市中西医结合医院,广东深圳518104 [3]深圳市宝安区疾病预防控制中心,广东深圳518101

出　　处：《中华卫生杀虫药械》2025年第2期176-179,共4页Chinese Journal of Hygienic Insecticides and Equipments

基　　金：深圳市宝安区科技创新局医疗卫生科研项目(2023JD135)。

摘　　要：目的了解深圳市宝安区2006—2023年恙虫病的时空分布流行特征。方法以传染病网络直报系统中2006—2023年宝安区报告发病的205例恙虫病为研究对象,采用Joinpoint v5.2.0软件进行回归分析,计算年度变化百分比(annual percentage change,APC)和平均年度变化百分比(average annual percentage change,AAPC)。采用SaTScan v10.2.1软件进行时空聚集性分析,计算窗口内外对数似然比(log-likelihood ratio,LLR)。结果2006—2023年,宝安区恙虫病整体呈上升趋势,2008—2013年发病率由0.016/10万上升到0.164/10万(APC=56.34%,t=2.98,P=0.015),2013—2023年发病率由0.164/10万上升到0.577/10万(APC=11.68%,t=3.10,P=0.013)。时空扫描显示,I类聚集区为西乡街道、新安街道、航城街道和福永街道,聚集时间为2016年5月1日至2023年11月30日(LLR=72.76,RR=5.66,P<0.001)。发病年龄最低为11月龄、最高为73岁,以51~60岁人群发病数最多,占22.44%(46/205)。职业以家务及待业为主,占35.61%(73/205)。结论宝安区近18年来恙虫病疫情散发,整体呈上升趋势,夏季高发,4个街道5—11月有时空聚集性,提示高发人群可能是中年人、家务及待业人员。Objective To investigate the spatial and temporal distribution and epidemiological characteristics of tsutsugamushi disease in Bao'an District,Shenzhen from 2006 to 2023.Methods A total of 205 cases of tsutsugamushi disease reported in Bao'an District from 2006 to 2023 in the online direct reporting system of infectious diseases were taken as the research objects,and the regression analysis was carried out by Joinpoint v5.2.0 software,and the annual percentage change(APC)and average annual percentage change(AAPC)were calculated.SaTScan v10.2.1 software was used to analyze the spatiotemporal aggregation,and the log-likelihood ratio(LLR)inside and outside the window was calculated.Results From 2006 to 2023,the incidence rate of tsutsugamushi disease in Bao'an District increased from 0.016/100000 to 0.164/100000 from 2008 to 2013(APC=56.34%,t=2.98,P=0.015),and from 0.164/100000 to 0.577/100000 from 2013 to 2023(APC=11.68%,t=3.10,P=0.013).The spatio-temporal scan showed that the Class I gathering areas were Xixiang Street,Xin'an Street,Hangcheng Street and Fuyong Street,and the gathering time was from May 1,2016 to November 30,2023(LLR=72.76,RR=5.66,P<0.001).The lowest age of onset was 11 months old and the highest was 73 years old,with the largest number of cases in people aged 51-60 years,accounting for 22.44%(46/205).Household chores and unemployed occupations were the main occupations,accounting for 35.61%(73/205).Conclusion In the past 18 years,the epidemic of tsutsugamushi disease in Bao'an District has been sporadic and has shown an upward trend as a whole,with a high incidence in summer,and there are spatiotemporal clusters in 4 streets from May to November,and the high-risk groups are middle-aged people,housekeepers and unemployed people.

关 键 词：恙虫病 Joinpoint回归分析 时空聚集性 流行特征 

分 类 号：R376.2[医药卫生—病原生物学]