中国中老年人群关节炎、社交活动和心理健康之间相互关系的横断面研究  

The relationship between arthritis,social activities,and mental health in middle-aged and elderly Chinese adults:a cross-sectional study

作　　者：黄长发 樊浩 魏泽 郝静 刘理金 刘苏 郑志发 刘菲 赵丽娜 吴志宏 HUANG Changfa;FAN Hao;WEI Ze;HAO Jing;LIU Lijin;LIU Su;ZHENG Zhifa;LIU Fei;ZHAO Lina;WU Zhihong(Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Department of Orthopaedics,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Stem Cell Platform,National Translational Medicine Facility,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;National Key Laboratory of Complex and Rare Diseases,Beijing 100730,China)

机构地区：[1]中国医学科学院、北京协和医学院,北京100730 [2]中国医学科学院、北京协和医学院、北京协和医院骨科,北京100730 [3]中国医学科学院、北京协和医学院、北京协和医院临床医学研究所、转化医学国家重大科技基础设施干细胞平台,北京100730 [4]疑难重症及罕见病全国重点实验室,北京100730

出　　处：《中华骨与关节外科杂志》2025年第4期350-356,共7页Chinese Journal of Bone and Joint Surgery

基　　金：国家重点研发计划(2022YFC2703901);国家自然科学基金青年科学基金(82402760);北京市自然科学基金青年项目(7244389);中国医学科学院医学与健康科技创新工程重大协同创新项目(2021-I2M-1-052);北京协和医院中央高水平医院临床科研专项重大公关计划(2022-PUMCH-D-002)。

摘　　要：目的:探讨中国中老年人群关节炎与心理健康的关联,并分析社交活动在这一关系中的潜在中介作用。方法:基于2020年中国健康与养老追踪调查(CHARLS)的数据,对19235名受访者进行横断面分析。采用logistic回归模型评估关节炎与心理健康之间的关联,并通过Bootstrap方法(模拟1000次)检验社交活动的中介效应。结果:关节炎与心理健康问题风险增加显著相关(OR=1.84,95%CI:1.529~2.234,P<0.001),同时,关节炎患者参与社交活动的可能性较低(OR=0.91,95%CI:0.854~0.973,P<0.05)。中介效应检验结果表明,社交活动在关节炎与心理健康之间的关系中存在显著中介作用(P<0.05)。结论:关节炎、社交活动和心理健康之间存在重要关联,提示社交活动可能对关节炎患者的心理健康状况有影响,但仍需要进一步验证以确定是否可作为潜在干预策略。Objective:To investigate the association between arthritis and mental health among middle-aged and elderly Chinese adults,and to explore the potential mediating role of social activities in this relationship.Methods:A cross-sectional study was conducted using data from the 2020 wave of the China Health and Retirement Longitudinal Study,including 19395 participants.Logistic regression models were used to evaluate the association between arthritis and mental health.The mediating effect of social activities was examined through bootstrap analysis with 1,000 replications.Results:Arthritis was significantly associated with increased risk of mental health problems(OR=1.84,95%CI:1.529-2.234,P<0.001).Additionally,individuals with arthritis were less likely to engage in social activities(OR=0.91,95%CI:0.854-0.973,P<0.05).Mediation analysis revealed a significant mediating role of social activities in the relationship between arthritis and mental health(P<0.05).Conclusions:There is a significant relationship between arthritis,social activities,and mental health in middle-aged and elderly Chinese adults.These findings suggest that promoting social engagement may be a potential intervention strategy to improve mental health in individuals with arthritis.

关 键 词：关节炎 心理健康 社交活动 中老年人 中介效应 

分 类 号：R684.3[医药卫生—骨科学] B844.4[医药卫生—外科学] D669.6[医药卫生—临床医学]