疾病参考模型的构建及其在卫生决策中的作用  

The Construction of Disease-Specific Reference Models and the Impact on Health Decision-Making

作　　者：潘婕 朱文涛[1] 官海静 Pan Jie;Zhu Wentao;Guan Haijing(Beijing University of Chinese Medicine,Beijing,100105,China;不详)

机构地区：[1]北京中医药大学,北京100105 [2]首都医科大学附属北京天坛医院,北京100070

出　　处：《中国卫生经济》2025年第3期9-14,共6页Chinese Health Economics

基　　金：国家自然科学基金青年项目(72104151)。

摘　　要：作为评估药物价值的工具,经济学评价模型在我国的卫生和医保决策中正发挥着越来越重要的作用。但是,由于经济学评价模型的不透明性和研究结果的不确定性,严重阻碍了研究证据的决策转化。构建疾病参考模型为解决这个问题提供了一种重要的思路和方法。首先,从疾病参考模型的概念出发,比较了其与传统经济学评价模型的差异,分析了构建疾病参考模型的关键环节;然后,以晚期肺癌、糖尿病和骨质疏松症为典型案例,阐述疾病参考模型的主要特点和发展现状;最后,分析疾病参考模型在我国发展的优势和挑战。文章系统梳理了疾病参考模型的方法与应用,这有助于探索经济学评价模型的未来发展方向,促进我国药物经济学的高质量发展和决策转化。As a tool for evaluating the value of drugs,Economic Evaluation(EE)models are playing an increasingly important role in healthcare and reimbursement decision-making in China.However,the lack of transparency and the uncertainty surrounding the results of these EE models have significantly hindered the translation of research evidence into policy decisions.Constructing a disease reference model provides a critical approach to address these challenges.First,starting from the concept of disease reference model,it compares its differences with traditional economics evaluation models and analyzes the key steps involved in their construction;secondly,it takes advanced lung cancer,diabetes mellitus,and osteoporosis as typical cases to illustrate the main features and the current development of disease reference models;and it finally analyzes the advantages and challenges of the development of disease reference models in China.By systematically reviewing the methods and applications of disease reference models,it contributes to the exploration of future directions for economic evaluation models and promotes the high-quality development and decision-making translation of pharmacoeconomics in China.

关 键 词：药物经济学 疾病参考模型 卫生决策 研究证据 

分 类 号：R1-9[医药卫生—公共卫生与预防医学] R-012