眼针疗法联合揿针治疗帕金森病便秘的临床研究  

Clinical Study of Eye Acupuncture Combined with Thumbtack Needling in Treatment of Parkinson's Disease-Related Constipation

作　　者：吴迪 杨禾财 张海婷 张云丽 刘鹏[2,3] WU Di;YANG Hecai;ZHANG Haiting;ZHANG Yunli;LIU Peng(Heilongjiang Provincial Social Rehabilitation Hospital,Harbin 150001,China;Heilongjiang University of Chinese Medicine,Harbin 150040,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江省社会康复医院,黑龙江哈尔滨150001 [2]黑龙江中医药大学,黑龙江哈尔滨150040 [3]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040

出　　处：《针灸临床杂志》2025年第4期12-17,共6页Journal of Clinical Acupuncture and Moxibustion

基　　金：黑龙江省自然科学基金项目联合引导项目,编号:LH2022H083;黑龙江省卫生健康委科技计划,编号:20210303070174;黑龙江省中医药科研项目,编号:ZHY2024-271。

摘　　要：目的:观察眼针疗法联合揿针治疗帕金森便秘的临床疗效。方法:选取2020年—2022年于本院针灸科住院部就诊的帕金森便秘患者60例,通过随机对照表法分为常规针刺组及联合疗法组,每组各30例。两组均在接受常规抗帕金森药物治疗的基础上进行相应干预。常规针刺组按照教科书规范进行取穴及操作。联合疗法组在常规针刺的基础上,选用眼针(肝区、脾区、胃区和大肠区)针刺1次/d;并于肝、脾、胃及大肠之背俞穴贴附揿针,1次/2 d更换。在治疗前及第14天末次治疗后,分别测评两组所有患者的慢性便秘严重度评分量表(CSS)、粪便性状(Bristol)评分、便秘患者生存质量量表(PAC-QOL)、汉密尔顿抑郁量表(HAMD)、5-羟色胺和胃促生长素及胃动素的水平,最终分别评定两组的临床效果。结果:干预治疗后,两组量表评分(即CSS、Bristol评分、PAC-QOL及HAMD-24)分数均较治疗前显著降低,差异具有统计学意义(P<0.05),且联合疗法组的评分要显著低于常规针刺组,差异具有统计学意义(P<0.05);5-羟色胺、胃促生长素及胃动素的水平均治疗较前显著上升(P<0.05);联合疗法组的3种激素水平均显著高于常规针刺组,差异具有统计学意义(P<0.05),联合疗法组总有效率为83.33%(25/30),优于常规针刺组的总有效率70.00%(21/30),差异具有统计学意义(P<0.05)。结论:眼针疗法联合揿针可眼-脑-肠同治,显著改善帕金森便秘患者的大便性状,缓解便秘症状,疏解心境抑郁,提升生活质量,其机理可能与调节5-羟色胺及胃肠激素中的胃促生长素与胃动素水平相关。Objective:To observe the clinical efficacy of eye acupuncture combined with thumbtack needling in treatment of Parkinson's disease(PD)-related constipation.Methods:60 patients with PD-related constipation were randomly divided into the conventional acupuncture group and the combined therapy group,with 30 cases in each group.Both groups were treated with conventional medications for PD.The conventional acupuncture group was treated with needling points and operations according to the textbook specifications;on which basis,the combined therapy group was treated with eye needling Liver zone,Spleen zone,Stomach zone,and Large intestine zone,once per day;the thumbtack needling was also applied to Ganshu(BL18),Pishu(BL20),Weishu(BL21),and Dachangshu(BL25) in the combined therapy group,once every other day.The chronic constipation severity rating scale(CSS) score,stool characteristics(Bristol) score,patient assessment of constipation quality of life scale(PAC-QOL) score,Hamilton's depression scale(HAMD) score,and the levels of 5-HT,ghrelin and motilin were measured before the treatment and after 14 days of the treatment.The clinical efficacy was compared between the two groups.Results:The CSS score,Bristol score,PAC-QOL score,and HAMD-24 score were all significantly decreased after the treatment compared to those before the treatment in both groups(P<0.05),and the scores in the combined therapy group were significantly lower than those in the conventional acupuncture group(P<0.05).The levels of 5-HT,ghrelin and motilin were significantly increased after the treatment compared to those before the treatment in the two groups(P<0.05),and the increases were more significant in the combined therapy group than those in the conventional acupuncture group(P<0.05).The total effective rate was 83.33%(25/30) in the combined therapy group,which was higher than 70.00%(21/30) in the conventional acupuncture group(P<0.05).Conclusion:The combination of eye acupuncture and thumbtack needling can significantly improve stool properties,re

关 键 词：帕金森病 便秘 眼针 揿针 

分 类 号：R246.6[医药卫生—针灸推拿学]