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作 者:尹瑞楠 关莹[2] 唐祎周 王婷 于国强 田欣欣 王艳丽 YIN Ruinan;GUAN Ying;TANG Yizhou;WANG Ting;YU Guoqiang;TIAN Xinxin;WANG Yanli(Heilongjiang University of Chinese Medicine,Harbin 150040,China;The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150001,China;Heilongjiang Nursing College,Harbin 150399,China)
机构地区:[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第二医院,黑龙江哈尔滨150001 [3]黑龙江护理高等专科学校,黑龙江哈尔滨150399
出 处:《针灸临床杂志》2025年第3期29-34,共6页Journal of Clinical Acupuncture and Moxibustion
基 金:国家自然科学基金面上项目,编号:82074539;国家自然科学基金青年项目,编号:82004439;孙申田青年人才基金,编号:2020KY-12;黑龙江省国医大师学术思想传承科研课题,编号:GY2022-19。
摘 要:目的:探讨经颅重复针刺手法联合化瘀通络灸对血管性痴呆患者认知功能及脑血流灌注的影响。方法:选取60例血管性痴呆患者随机分为对照组和治疗组,各30例。两组患者均服用控制自身基础疾病药物及盐酸多奈哌齐片。对照组采用常规针刺联合化瘀通络灸治疗,治疗组采用经颅重复针刺手法联合化瘀通络灸治疗,治疗周期为1个月。评估两组治疗前后MMSE、MoCA量表评分、Hcy浓度及TCD检查情况,并对比两组临床疗效。结果:两组治疗后MMSE、MoCA量表评分均升高,差异具有统计学意义(P<0.05),且治疗组优于对照组(P<0.05)。治疗组总有效率优于对照组,差异具有统计学意义(P<0.05)。治疗后两组Hcy浓度均下降,差异具有统计学意义(P<0.05),治疗组疗效更为明显。TCD检查提示,两组治疗后脑血流速度均较治疗前明显提高,差异具有统计学意义(P<0.05),且治疗组高于对照组,差异具有统计学意义(P<0.05)。结论:经颅重复针刺手法联合化瘀通络灸可显著提升脑部血液循环,提高MMSE及MoCA评分,改善其认知功能,为临床应用提供新思路。Objective:To investigate the effect of transcranial repeated acupuncture combined with Huayu Tongluo moxibustion on cognitive function and cerebral blood flow perfusion in patients with vascular dementia.Methods:60 patients with vascular dementia were randomly divided into the control group and the treatment group,with 30 patients in each group.Both groups were given routine medication to control basic diseases and Donepezil Hydrochloride Tablet.The control group was treated with conventional acupuncture combined with Huayu Tongluo moxibustion,and the treatment group was treated with repeated transcranial acupuncture combined with Huayu Tongluo moxibustion.The treatment duration was one month.The scores of mini-mental state examination(MMSE)scale and Montreal cognitive assessment(MoCA)scale,Hcy concentration and transcranial Doppler ultrasound(TCD)examination were evaluated before and after the treatment in the two groups,and the clinical efficacy was compared between the two groups.Results:The total effective rate was higher in the treatment group than that in the control group(P<0.05).The scores of MMSE scale and MoCA scale were increased after the treatment in the two groups(P<0.05),and the increases were more significant in the treatment group than those in the control group(P<0.05).The Hcy concentration was decreased after the treatment in the two groups(P<0.05),and the effect of the treatment group was more obvious.TCD examination showed that the cerebral blood flow velocity was significantly increased after the treatment in the two groups(P<0.05),and the velocity of the treatment group was higher than that of the control group(P<0.05).Conclusion:Transcranial repeated acupuncture combined with Huayu Tongluo moxibustion can significantly improve cerebral blood circulation,the scores of MMSE and MoCA,and the cognitive function of the patients,which provides new ideas for its clinical application.
关 键 词:血管性痴呆 经颅重复针刺 化瘀通络灸 认知功能评估量表 简易精神状态检查量表 经颅多普勒超声
分 类 号:R246.6[医药卫生—针灸推拿学]
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