电针左侧肢体经穴对双侧初级运动皮层兴奋性作用研究  

Effect of Electro-Needling Points of Left Limb on Excitability of Bilateral Primary Motor Cortex

作　　者：许民栋 徐晶 赵嘉怡 许能贵 易玮 王琳 韩为 XU Mindong;XU Jing;ZHAO Jiayi;XU Nenggui;YI Wei;WANG Lin;HAN Wei(Clinical Medical College of Acupuncture Moxibustion and Rehabilitation,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou 510100,China)

机构地区：[1]广州中医药大学针灸康复临床医学院,广东广州510006 [2]广州医科大学附属脑科医院,广东广州510100

出　　处：《针灸临床杂志》2025年第3期40-45,共6页Journal of Clinical Acupuncture and Moxibustion

基　　金：国家自然科学基金,编号:81904297、82374573;广东省重点领域研发计划,编号:2020B1111100008。

摘　　要：目的:探究生理状态下电针左侧肢体经穴对双侧M1脑区兴奋性的影响。方法:在符合纳排标准的基础上,共纳入健康受试者40例,随机分成电针组和假电针组,每组20例。在运用安慰针管的基础上电针或假电针刺激左侧肢体曲池穴、合谷穴、足三里穴与冲阳穴,并连接电针仪,留针15 min。干预前后分别用TMS刺激双侧M1脑区,记录以M1脑区所支配的大鱼际肌为靶肌的MEP和RMT。结果:电针组干预后双侧MEP波幅上升均有显著统计学意义(P<0.01);而假电针组差异无统计学意义(P>0.05)。两组干预前后双侧MEP潜伏期的差异均无统计学差异(P>0.05)。电针组干预后双侧RMT下降差异有统计学意义(P<0.05),而假电针组差异无统计学意义(P>0.05)。两组左侧M1脑区干预前后的MEP波幅差值均大于右侧,差异均无统计学意义(P>0.05)。两组左侧M1脑区干预前后的RMT差值均大于右侧,其中电针组差异有统计学意义(P<0.05)。结论:在生理状态下,电针左侧肢体阳明经穴对人类双侧M1脑区兴奋性均有一定的促进作用,且可能存在对左、右脑区偏侧性的差异。Objective:To explore the effect of electro-needling the points of the left limb on the excitability of the bilateral primary motor cortex(M1)under physiological conditions.Methods:On the basis of meeting the exclusion and inclusion criteria,a total of 40 healthy subjects were included in this study,which were randomized into the electro-acupuncture(EA)group and the sham EA group,with 20 cases in each group.The EA group was treated with electro-needling Quchi(LI11),Zusanli(ST36),Hegu(LI4)and Chongyang(ST42)of the left limb.In the sham EA group,K Streitberger placebo was placed on the skin of LI11,ST36,LI4 and ST42 of the left limb without inserting into the skin.The needle retention lasted 15 minutes in both groups.The RMT and MEP of the thenar muscles induced by TMS were recorded before and after the intervention in the two groups.Results:In terms of the amplitude of MEP,it was significantly increased on the both sides in the EA group(P<0.01);however,no significant difference was shown in the sham EA group(P>0.05).In terms of the latency of MEP,no significant differences were shown in both groups(P>0.05).In terms of RMT,it was significantly decreased in the EA group(P<0.05);however,no significant difference was shown in the sham EA group(P>0.05).In terms of unilateral effects on excitability in the left and right M1 brain regions,the difference in MEP amplitude between before and after the intervention in the left M1 brain area was greater than that on the right side in both groups,but there was no statistical difference(P>0.05);the difference in RMT between before and after the intervention in the left M1 brain area was greater than that on the right side,with statistical differences observed in the EA group(P<0.05).Conclusion:Under physiological conditions,electro-needling points of the left limb can promote the excitability of the bilateral M1 brain region,which shows difference between the left and right brain regions.

关 键 词：电针 经颅磁刺激 初级运动皮层 兴奋性 

分 类 号：R245.97[医药卫生—针灸推拿学]