五脏俞穴位埋线治疗乳腺癌患者癌因性疲乏的临床研究  

Clinical Study on Five-Zang Acupoints Catgut Embedding in Treatment of Breast Cancer Related Fatigue

作　　者：王园园 杨添淞[1,2] 孙晓伟[1,2] WANG Yuanyuan;YANG Tiansong;SUN Xiaowei(Heilongjiang University of Chinese Medicine,Harbin 150040,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040

出　　处：《针灸临床杂志》2025年第3期46-51,共6页Journal of Clinical Acupuncture and Moxibustion

基　　金：国家自然科学基金面上项目,编号:82074539。

摘　　要：目的:研究五脏俞穴位埋线治疗乳腺癌患者癌因性疲乏的临床疗效及对生活质量、免疫功能的影响。方法:将符合本研究的60例患者随机分为常规针刺对照组和五脏俞穴位埋线治疗组,每组30例。对照组每周治疗6 d,停针1 d,7 d为1个疗程,共治疗4个疗程。治疗组7 d埋线1次,连续埋线4次。比较两组治疗前后癌症疲乏量表(CFS)、Karnofsky功能状态评分(KPS)、匹兹堡失眠质量量表评分(PSQI)、中医症候评分和免疫功能指标。结果:治疗后,两组患者CFS评分、PSQI评分和中医症候积分较治疗前均降低,差异具有统计学意义(P<0.01),且治疗组降低更明显,差异具有统计学意义(P<0.05);KPS评分均较治疗前升高,差异具有统计学意义(P<0.01),且治疗组优于对照组,差异具有统计学意义(P<0.05);两组CD3^(+)、CD4^(+)和CD4^(+)/CD8^(+)水平均上升,差异具有统计学意义(P<0.01),且治疗组改善更明显,差异具有统计学意义(P<0.05)。结论:五脏俞穴位埋线治疗乳腺癌患者癌因性疲乏具有较好的临床疗效,能够明显减轻或消除患者疲乏状态,改善睡眠质量,具有临床应用价值。Objective:To investigate the clinical curative efficacy of five-Zang acupoints catgut embedding in treatment of breast cancer related fatigue and to observe its influence to life quality and immune function of the patients.Methods:60 patients who met the inclusion criteria were randomly divided into the control group and the treatment group,with 30 cases in each group.The control group was treated by conventional acupuncture,once a day,6 times per week for four weeks;the treatment group was treated by five-Zang acupoints catgut embedding,once per 7 days for 4 times.The scores of Cancer Fatigue Scale(CFS),Karnofsky Performance Status(KPS),Pittsburgh Sleep Quality Index(PSQI)and TCM symptoms,as well as the indexes of immune function were compared between before and after the treatment in the two groups.Results:The scores of CFS,PSQI and TCM symptoms were decreased after the treatment compared with those before the treatment in the two groups(P<0.05),and the decreases were more significant in the treatment group than those in the control group(P<0.05).The KPS scores were higher after the treatment than those before the treatment in the two groups(P<0.05),and the KPS score was higher in the treatment group than that in the control group after the treatment(P<0.05).The levels of CD3^(+),CD4^(+),and CD4^(+)/CD8^(+)were increased after the treatment compared with those before the treatment in the two groups(P<0.05),and the increases of the treatment group were more significant than those of the control group(P<0.05).Conclusion:Five-Zang acupoints catgut embedding has a good clinical effect on breast cancer related fatigue,which can significantly reduce or eliminate the fatigue state of the patients and improve the quality of sleep,which possesses significant clinical application value.

关 键 词：乳腺癌 五脏俞 穴位埋线 癌因性疲乏 

分 类 号：R246.5[医药卫生—针灸推拿学]