降主动脉近脊柱侧钙化与胸椎骨质增生相关性  

Correlation between Calcification of the Descending Aorta Close to the Spine and Osteophyte Formation in the Thoracic Vertebrae

作　　者：李玉花[1] 于克文 罗昕[1] 刘伟 李波[3] LI Yu-hua;Yu Ke-wen;Luo Xin;LIU Wei;Li Bo(Department of Radiology,Zibo Central Hospital,Zibo 255036,Shandong Province,China;Department of Internal Medicine,Zibo Maternal and Child Health Hospital,Zibo 255000,Shandong Province,China;Department of Cardiology,Zibo Central Hospital,Zibo 255036,Shandong Province,China)

机构地区：[1]淄博市中心医院放射科,山东淄博255036 [2]淄博市妇幼保健医院内科,山东淄博255000 [3]淄博市中心医院心内科,山东淄博255036

出　　处：《中国CT和MRI杂志》2025年第4期164-167,共4页Chinese Journal of CT and MRI

基　　金：2023年淄博市医药卫生科研项目(20230901079);山东省重点研发计划项目(2018GSF118140)。

摘　　要：目的探讨基于CT的降主动脉近脊柱侧钙化与胸椎椎体骨质增生相关性。方法收集232例观察对象一般资料、生化指标及基于CT的骨密度定量指标。CT图像将降主动脉钙化分为近肺(A)、近纵隔(B)及近脊柱(C)区并分组,1组:无钙化,2组:仅A区钙化,3组:仅B区钙化,4组:仅C区钙化,5组:A+B区钙化,6组:A+C区钙化,7组:B+C区钙化,8组:A+B+C区钙化。比较不同分组间各指标的差异;比较不同组间动脉钙化率的差异;动脉钙化积分与各指标相关性分析;筛选降主动脉近脊柱侧钙化的风险因子,绘制ROC曲线,建立预测模型。结果4组与1组间年龄、骨赘积分及松质骨密度有统计学差异,4组与2组骨赘积分及动脉钙化率有统计学差异。年龄及骨赘积分与降主动脉近脊柱侧钙化积分显著正相关,联合应用骨赘积分与年龄对降主动脉近脊柱侧钙化具有更高AUC值(0.883)。结论降主动脉近脊柱侧钙化率最高,胸椎椎体骨赘积分与其显著相关,联合骨赘积分与年龄对其有更高预测价值。Objective To explore the correlation between calcification of the descending aorta close to the spine based on CT and osteophyte formation in the thoracic vertebrae.Methods Collected general information,biochemical indicators,and quantitative bone density indicators based on CT for 232 subjects.CT images were divided into three regions for aortic calcification:near the lung(A),near the mediastinum(B),and near the spine(C),and subjects were grouped accordingly:Group 1:No calcification,Group 2:Calcification only in region A,Group 3:Calcification only in region B,Group 4:Calcification only in region C,Group 5:Calcification in regions A+B,Group 6:Calcification in regions A+C,Group 7:Calcification in regions B+C,Group 8:Calcification in regions A+B+C.Differences in various indicators between groups were compared;differences in arterial calcification rates between groups were compared;correlation analysis between arterial calcification scores and various indicators was performed;risk factors for calcification of the descending aorta close to the spine were screened,ROC curves were plotted,and a predictive model was established.Results There were statistically significant differences in age,osteophyte scores,and trabecular bone density between Group 4 and Group 1,and between Group 4 and Group 2 in terms of osteophyte scores and arterial calcification rates.Age and osteophyte scores were significantly positively correlated with calcification scores of the descending aorta close to the spine,and the combined use of osteophyte scores and age had a higher AUC value(0.883)for predicting calcification of the descending aorta close to the spine.Conclusion The calcification rate of the descending aorta close to the spine is the highest,and it is significantly correlated with thoracic vertebral osteophyte scores,with the combined use of osteophyte scores and age having a higher predictive value.

关 键 词：骨质增生 骨赘 钙化积分 动脉硬化 

分 类 号：R543.12[医药卫生—心血管疾病]