环泊酚复合瑞芬太尼在无痛胃镜检查中的应用  

The Application of Propofol Combined with Remifentanil in Painless Gastroscopy Examination

作　　者：宋建阳 陈毓铭 苏志辉 翁雪云 SONG Jian-yang;CHEN Yu-ming;SU Zhi-hui;WENG Xue-yun(Department of Anesthesiology,Affiliated People's Hospital of Quanzhou Medical College,Quanzhou 362000,Fujian Province,China)

机构地区：[1]泉州市医学高等专科学校附属人民医院麻醉科,福建泉州362000

出　　处：《罕少疾病杂志》2025年第4期126-128,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的观察环泊酚复合瑞芬太尼在无痛胃镜检查中的应用。方法选择本院于2022年5月至2023年1月收治的疑似消化道疾病拟行无痛胃镜检查患者96例,依据随机数表法分为对照组与实验组各48例。两组胃镜检查方法相同,对照组麻醉方案为丙泊酚+瑞芬太尼,实验组麻醉方案为环泊酚+瑞芬太尼。记录麻醉相关指标与不良反应发生率,分别于麻醉给药前(T0)、麻醉5min后(T1)、胃镜经过咽喉部(T2)、胃镜检查结束(T3)、患者苏醒(T4)记录生命体征监护仪血气分析值。结果实验组麻醉生效时间、苏醒时间、胃镜检查时间、离开诊室时间均低于对照组(P<0.05)。T0与T4时两组血气分析值(SpO2、MMP、HR)无明显差异(P>0.05),T1、T2、T3时实验组血气分析值均高于对照组(P<0.05);两组血气分析值均呈下降然后曲线回升,且实验组变化幅度小于对照组(P<0.05)。对照组总不良反应率为18.75%,略高于实验组10.42%,但两组差异不显著(P>0.05)。结论在无痛胃镜检查患者中使用环泊酚复合瑞芬太尼麻醉,具有生效时间快、复苏时间短及血气分析值更稳定的优势。Objective To observe the application of propofol combined with remifentanil in painless gastroscopy.Methods Ninety six patients with suspected digestive tract diseases who were scheduled to undergo painless gastroscopy examination in our hospital from May 2022 to January 2023 were selected.They were randomly divided into a control group and an experimental group,with 48 cases in each group,using a random number table method.The two groups of gastroscopy examination methods are the same.The control group is anesthetized with propofol+remifentanil,while the experimental group is anesthetized with propofol+remifentanil.Record anesthesia related indicators and incidence of adverse reactions,and record vital sign monitor blood gas analysis values before anesthesia administration(T0),5 minutes after anesthesia(T1),gastroscopy passing through the throat(T2),gastroscopy ending(T3),and patient awakening(T4).Results The effective time of anesthesia,awakening time,gastroscopy examination time,and departure time of the experimental group were all lower than those of the control group(P<0.05).There was no significant difference in blood gas analysis values(SpO2,MMP,HR)between the two groups at T0 and T4(P>0.05).The blood gas analysis values of the experimental group were higher than those of the control group at T1,T2,and T3(P<0.05).The blood gas analysis values of both groups showed a decrease followed by a rebound in the curve,and the amplitude of change in the experimental group was smaller than that in the control group(P<0.05).The total adverse reaction rate of the control group was 18.75%,slightly higher than that of the experimental group at 10.42%,but the two groups were not significantly different(P>0.05).Conclusion The use of propofol combined with remifentanil anesthesia in patients undergoing painless gastroscopy has the advantages of fast effective time,short recovery time,and more stable blood gas analysis values.

关 键 词：环泊酚 瑞芬太尼 麻醉 无痛胃镜检查 消化道疾病 

分 类 号：R614.3[医药卫生—麻醉学]