急性中毒合并院内感染相关情况及危险因素研究  

The Surveys of the Clinical Conditions and Risk Factors in Acute Poisoning Patients with Nosocomial Infections

作　　者：王如 WANG Ru(Emergency Department,Jiujiang No.1 People’s Hospital,Jiujiang 332000,Jiangxi Province,China)

机构地区：[1]九江市第一人民医院急诊科,江西九江332000

出　　处：《罕少疾病杂志》2025年第4期158-160,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨急性中毒患者合并院内感染相关情况及危险因素。方法本研究选取2021年1月至2023年1月我院1578例急性中毒患者,所有患者均接受对症急救治疗,根据住院期间有无院内感染进行分组,收集两组一般资料,将有差异资料带入Logistic回归方程计算,分析院内感染发生的相关因素。结果1578例急性中毒患者中发生院内感染者136例、发生率8.62%,根据感染分布情况显示单纯肺部感染占比最多,达到33.09%;不同中毒类型的感染占比中,以急性强酸、强碱类中毒患者感染率最高,达到22.79%;将136例发生院内感染的患者纳入感染组,1442例未发生院内感染的患者纳入未感染组,两组在住院时间、合并基础疾病、使用呼吸机和留置导尿管、留置胃管、意识状态、抗生素的使用方面存在明显差异(P<0.05)。经Logistic回归方程分析显示:住院时间≥7d、合并基础疾病、使用呼吸机和留置导尿管/胃管、昏迷、常规使用抗生素均是导致急性中毒患者发生院内感染的危险因素(均OR>1,均P<0.05)。结论急性中毒患者存在一定的院内感染发生风险,主要以肺部感染最为常见,导致感染的危险因素与患者住院时长、自身基础疾病、意识状态以及呼吸机的使用和侵袭性操作有关,故而在患者住院期间需加强对危险因素的护理干预,以达到减少院内感染发生的目的。Objective To study the clinical conditions and risk factors in acute poisoning patients with nosocomial infections.Methods 1578 acute poisoning patients of undergoing the symptomatic treatment(2021.01-2023.01)were selected.According to the occurrences of noscomial infection,patients were assigned to infection group and non-infection group.The general data was acquired;Logistic regression equation was used to analyze the risk factors of the patient’s nosocomial infections.Results 136 patients were found with the nosocomial infections(8.62%);the ratios of the simple pulmonary infection were the highest(33.09%);the ratios of nosocomial infections among the acute strong acid and alkali poisoning patients were the highest(22.79%).136 patients with nosocomial infection were set as the infection group;1442 patients without nosocomial infection were set as the non-infection group.There were significant between-group differences about the hospital stays,the complications of underlying disease,the usage of ventilator,indwelling catheter and indwelling gastric tube,the conscious state and the antibiotics usage(P<0.05);Logistic regression equation indicated that the risk factors of nosocomial infection included the hospital stays≥7d,the complications of underlying disease,the usage of ventilator,indwelling catheter and indwelling gastric tube,coma and the routine antibiotic usage(OR>1,P<0.05).Conclusion The acute poisoning patients might be complicated with nosocomial infection,especially with the pulmonary infection.The risk factors of acute poisoning patients with nosocomial infection are the long hospital stays,the complications of underlying disease,the conscious state,the usage of ventilator and the invasive operation.Therefore,the specific nursing interventions shall be strengthened to reduce the occurrences of nosocomial infections.

关 键 词：急性中毒 院内感染 危险因素 

分 类 号：R825.92[医药卫生—临床医学]