基于心肺运动试验分析房颤患者经导管射频消融术后的心肺功能  

Analysis of Cardiopulmonary Function in Patients with Atrial Fibrillation After Catheter Radiofrequency Ablation Based on Cardiopulmonary Exercise Testing

作　　者：赵丹莉 葛适文 岳新杰 袁丽霞[1] ZHAO Danli;GE Shiwen;YUE Xinjie;YUAN Lixia(Department of Cardiac Rehabilitation,The Seventh People's Hospital of Zhengzhou,Zhengzhou Henan 450016,China;Department of Cardiology,The Seventh People's Hospital of Zhengzhou,Zhengzhou Henan 450016,China)

机构地区：[1]郑州市第七人民医院心脏康复科,河南郑州450016 [2]郑州市第七人民医院心内科,河南郑州450016

出　　处：《临床研究》2025年第4期44-47,共4页Clinical Research

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20240909)。

摘　　要：目的通过心肺运动试验(CPET)分析房颤患者经导管射频消融术(RFCA)后的心肺功能变化。方法回顾性分析2023年3月至2024年6月期间郑州市第七人民医院收治且进行RFCA术的60例房颤患者的病例资料,作为病例组,采用运动心肺功能测试系统进行CPET,另选取同期进行CPET检查的30例健康体检者为对照组,分析房颤患者RFCA术后心肺功能的变化,并对比两组患者心肺功能参数。结果术前,病例组的峰值摄氧量(VO_(2)peak)、无氧阈(AT)、峰值氧脉搏(O_(2)Ppeak)和最大运动负荷(Wmax)低于对照组,差异有统计学意义(P<0.05),二氧化碳通气当量斜率(VE/VCO_(2))高于对照组,差异有统计学意义(P<0.05);病例组房颤RFCA术后3个月的VO_(2)peak、AT、O_(2)Ppeak和Wmax显著高于术前,VE/VCO_(2)斜率低于术前,差异有统计学意义(P<0.05)。病例组患者术后3个月的VO_(2)peak、AT、O_(2)Ppeak、Wmax均低于对照组,VE/VCO_(2)斜率高于对照组,差异有统计学意义(P<0.05)。结论房颤患者的心肺功能显著下降,RFCA术能有效改善房颤患者术后的心肺功能,但与健康人群相比仍存在一定的差距。Objective To analyze changes in cardiopulmonary function in patients with atrial fibrillation after catheter radiofrequency ablation(RFCA)using cardiopulmonary exercise testing(CPET).Methods A retrospective analysis was conducted on the case data of 60 patients with atrial fibrillation who underwent RFCA at The Seventh People's Hospital of Zhengzhou from March 2023 to June 2024.These patients constituted the case group,and their cardiopulmonary function was assessed using a CPET.Additionally,30 healthy individuals who underwent CPET during the same period were selected as the control group.Changes in cardiopulmonary function of atrial fibrillation patients post-RFCA were analyzed,and cardiopulmonary function parameters were compared between the two groups.Results Before surgery,the case group had lower peak oxygen uptake(VO_(2)peak),anaerobic threshold(AT),peak oxygen pulse(O_(2)Ppeak),and maximum exercise capacity(Wmax)compared to the control group,with statistically significant differences(P<0.05).Their ventilatory equivalent for carbon dioxide(VE/VCO_(2))slope was higher than that of the control group,with statistical significance(P<0.05).Three months after the RFCA procedure,the case group showed significant improvements in VO_(2)peak,AT,O_(2)Ppeak,and Wmax,with a reduction in VE/VCO_(2) slope compared to pre-surgery,with statistically significant differences(P<0.05).However,three months postsurgery,the case group still had lower VO_(2)peak,AT,O_(2)Ppeak,and Wmax,and a higher VE/VCO_(2) slope compared to the control group,all with statistically significant differences(P<0.05).Conclusion Cardiopulmonary function is significantly reduced in patients with atrial fibrillation.RFCA can effectively improve post-operative cardiopulmonary function in these patients,but a gap remains when compared to healthy individuals.

关 键 词：心房颤动 经导管射频消融术 心肺运动试验 心肺功能 

分 类 号：R541.7[医药卫生—心血管疾病]