泡沫硬化配合射频消融术对下肢静脉曲张患者疼痛及血流动力学的影响  

Effects of foam sclerotherapy combined with radiofrequency ablation on pain and hemodynamics in patients with varicose veins of lower extremity

作　　者：陈立文 袁启东 CHEN Liwen;YUAN Qidong(Department of Vascular Surgery,the Third People’s Hospital of He’nan Province,Zhengzhou 450000,China)

机构地区：[1]河南省直第三人民医院血管外科,郑州450000

出　　处：《上海医药》2025年第3期41-43,56,共4页Shanghai Medical & Pharmaceutical Journal

基　　金：河南省医学攻关计划(联合共建)项目(LHGJ20190857)。

摘　　要：目的:探讨超声引导下泡沫硬化配合射频消融术对下肢静脉曲张(VVLE)患者疼痛程度及血流动力学的影响。方法:将91例VVLE患者以抽签法分为对照组(46例)和研究组(45例),对照组予泡沫硬化治疗,研究组予泡沫硬化配合射频消融术治疗,对比两组的疗效、疼痛程度、血流动力学及凝血功能。结果:研究组的总有效率显著高于对照组(P<0.05),视觉模拟量表(VAS)评分、凝血功能指标显著低于对照组(P<0.05);两组患者的血流动力学无显著差异(P>0.05)。结论:VVLE患者采用超声引导下泡沫硬化配合射频消融术治疗效果较好,可减轻患者疼痛,改善凝血功能,且对血流动力学影响小。Objective:To investigate the clinical efficacy and hemodynamic safety of ultrasound-guided foam sclerotherapy(UGFS)combined with adjunctive radiofrequency ablationn(RFA)in patients with varicose veins of lower extremity(VVLE).Methods:Ninety-one VVLE patients were randomly allocated to either a control group(46 cases)or a study group(45 cases).The control group received UGFS and the study group underwent UGFS combined with RFA.The efficacy,pain score,hemodynamic parameters and coagulation function were compared between the two groups.Results:The study group demonstrated a significantly higher overall efficacy rate,along with significantly lower VAS scores and improved coagulation parameters compared to the control group(P<0.05).No significant differences in hemodynamic values were observed between the two groups(P>0.05).Conclusion:UGFS combined with RFA demonstrates significant clinical efficacy for treating VVLE,with reduced pain scores,improved coagulation parameters,and minimal impact on hemodynamic parameters.

关 键 词：下肢静脉曲张 超声引导下泡沫硬化 射频消融术 疼痛程度 血流动力学参数 

分 类 号：R454.1[医药卫生—治疗学] R543.6[医药卫生—临床医学]