中西医治疗PCI术后支架内再狭窄的研究进展  

Research Progress of Treatment of In-Stent Restenosis after PCI with Traditional Chinese and Western Medicine

作　　者：乃比江·麦麦提依明 安冬青[2] NAIBIJIANG Maimaitiyiming;AN Dongqing(The College of Traditional Chinese Medicine,Xinjiang Medical University,Urumqi 830011,China;Department of Cardiology,Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University,Urumqi 830000,China)

机构地区：[1]新疆医科大学中医学院,乌鲁木齐830011 [2]新疆医科大学附属中医医院心内科,乌鲁木齐830000

出　　处：《医学综述》2025年第9期1128-1132,共5页Medical Recapitulate

摘　　要：目前,在经皮冠状动脉介入治疗术后支架内再狭窄(ISR)的治疗上,中西医均取得一定进展。西医治疗ISR不仅可采用药物洗脱支架、研发新型药物涂层及改进支架材料以降低再狭窄率,还可规范药物治疗和使用血管内放疗等新技术。中医认为其与气虚血瘀、痰瘀互结等相关,运用活血化瘀、理气化痰等中药复方,改善血液流变学,抑制血管平滑肌细胞过度增殖,从而降低ISR风险。此外,针灸、穴位贴敷等外治法可调节机体经络气血、改善血管内皮功能。而中西医结合可协同增效,降低ISR的发生率,提高患者生活质量。未来,可深入探讨中药有效成分的作用机制及分子靶点,开展大规模临床研究,验证中西医结合方案的长期疗效,优化个体化治疗方案。Currently,certain progress has been made in both traditional Chinese medicine(TCM)and western medicine in the treatment of in-stent restenosis(ISR)following percutaneous coronary intervention.Western medicine treatment for ISR include not only the use of drug-eluting stents,the development of new drug coatings,and improvements in stent materials to reduce restenosis rates,but also standardized pharmacological therapies and the application of new technologies such as intravascular radiotherapy.TCM believes that it is related to qi deficiency,blood stasis,and phlegm stasis.By using TCM formulas such as promoting blood circulation,removing blood stasis,regulating qi and resolving phlegm,it can improve blood rheology,inhibit excessive proliferation of vascular smooth muscle cells,and reduce the risk of ISR.Besides,external therapies like acupuncture and acupoint application can regulate the body′s meridians and qi-blood flow,improving vascular endothelial function.The integration of TCM and western medicine can synergistically enhance the efficacy,reduce the incidence of ISR,and improve the patients′quality of life.In the future,further exploration of the mechanisms and molecular targets of active components in TCM,along with large-scale clinical studies can be done to validate the long-term efficacy of integrated TCM and western medicine approaches and to optimize individualized treatment plans.

关 键 词：冠心病 经皮冠状动脉介入治疗 支架内再狭窄 中西医治疗 

分 类 号：R541.4[医药卫生—心血管疾病]