超声引导下射频消融术治疗混合性甲状腺结节对患者术后应激及体积缩小率的影响  

Effect of Ultrasound-guided Radiofrequency Ablation on Postoperative Stress and Volume Reduction Rate of Patients with Mixed Thyroid Nodules

作　　者：闵永华 朱玉 江辉 MIN Yonghua;ZHU Yu;JIANG Hui(Department of Ultrasound Room,the Fifth Hospital of Nanchang,Nanchang 330000,China;不详)

机构地区：[1]南昌市第五医院彩超室,江西南昌330000 [2]南昌市第五医院超声科,江西南昌330000 [3]南昌市第五医院甲状腺科,江西南昌330000

出　　处：《中国医学创新》2025年第10期50-53,共4页Medical Innovation of China

摘　　要：目的:探究超声引导下射频消融术治疗混合性甲状腺结节对患者术后应激及体积缩小率的影响。方法:回顾性选择2022年1月—2023年4月南昌市第五医院收治的混合性甲状腺结节患者100例,依据不同微创治疗方法分为乙醇消融组(n=47)、射频消融组(n=53)。乙醇消融组采用超声引导下无水乙醇消融术,射频消融组采用超声引导下射频消融术。比较两组应激情况、结节体积缩小率及临床疗效。结果:相比乙醇消融组,射频消融组术后1dC反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平均低(P<0.05);相比乙醇消融组,射频消融组术后1、3、6、9、12个月结节体积缩小率均高(P<0.05);射频消融组总有效率为92.45%,高于乙醇消融组的72.34%(P<0.05)。结论:超声引导下射频消融术治疗混合性甲状腺结节可有效减轻患者应激反应,缩小结节体积。Objective:To explore the effect of ultrasound-guided radiofrequency ablation on postoperative stress and volume reduction rate of patients with mixed thyroid nodules.Method:A total of 100 patients with mixed thyroid nodules admitted to the Fifth Hospital of Nanchang from January 2022 to April 2023 were retrospectively selected and divided into ethanol ablation group(n=47)and radiofrequency ablation group(n=53)according to different microtraumatic treatment methods.The ethanol ablation group underwent ultrasound-guided anhydrous ethanol ablation,and the radiofrequency ablation group underwent ultrasound-guided radiofrequency ablation.The stress condition,nodules volume reduction rate and clinical efficacy of the two groups were compared.Result:Compared with ethanol ablation group,the levels of C reactive protein(CRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)1 d after surgery in radiofrequency ablation group were lower(P<0.05).Compared with ethanol ablation group,the nodules volume reduction rate in radiofrequency ablation group 1 month,3,6,9,12 months after surgery were higher(P<0.05).The total effective rate of radiofrequency ablation group was 92.45%,which was higher than 72.34%of ethanol ablation group(P<0.05).Conclusion:Ultrasound-guided radiofrequency ablation in the treatment of mixed thyroid nodules can effectively reduce the stress response of patients and reduce the nodules volume.

关 键 词：射频消融术 混合性甲状腺结节 术后应激 体积缩小率 

分 类 号：R581[医药卫生—内分泌]