机构地区:[1]菏泽市立医院内分泌科,山东菏泽274031 [2]菏泽市立医院临床药学科,山东菏泽274031
出 处:《中国医学创新》2025年第10期87-92,共6页Medical Innovation of China
基 金:菏泽市科技发展项目(2022YN40)。
摘 要:目的:探索中药足浴联合耳穴压豆辅助治疗痛性糖尿病周围神经病变(PDPN)的临床效果。方法:选取2022年1月—2023年12月菏泽市立医院内分泌科收治的76例PDPN患者,随机分为对照组和观察组,各38例。两组均给予基础治疗,对照组给予硫辛酸注射液联合甲钴胺片治疗,观察组在对照组治疗基础上给予中药足浴联合耳穴压豆治疗。比较两组治疗前后血糖控制情况、临床疗效及不良反应发生率。结果:观察组临床总有效率显著高于对照组,差异有统计学意义(P<0.05)。治疗后,两组空腹血糖(FPG)均低于治疗前,且观察组低于对照组(P<0.05);两组糖化血红蛋白(HbA1c)水平比较,差异无统计学意义(P>0.05)。治疗后,两组视觉模拟评分法(VAS)评分、密歇根神经病变筛查量表(MNSI)评分均低于治疗前,且观察组均低于对照组(P<0.05)。治疗后,两组正中神经、腓总神经的感觉神经传导速度(SNCV)和运动神经传导速度(MNCV)均高于治疗前,且观察组均高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:中药足浴联合耳穴压豆治疗PDPN的效果确切,优于单纯西药治疗。不仅可有效缓解疼痛,减轻病情的严重程度,改善神经传导速度,提高临床疗效,还能间接改善血糖控制,且安全性较高。Objective:To explore the clinical effect of traditional Chinese medicine foot bath combined with auricular point pressing therapy in the treatment of painful diabetic peripheral neuropathy(PDPN).Method:A total of 76 patients with PDPN treated in the Endocrinology Department of Heze Municipal Hospital from January 2022 to December 2023 were randomly divided into control group and observation group,with 38 patients in each group.Both groups were given basic treatment,the control group was given Lipoic Acid Injection combined with Mecobalamin Tablets,and the observation group was given traditional Chinese medicine foot bath combined with auricular point pressing therapy treatment on the basis of the control group.Blood glucose control before and after treatment,clinical efficacy and incidence of adverse reactions between the two groups were compared.Result:The total clinical effective rate of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).After treatment,fasting plasma glucose(FPG)in both groups were lower than those before treatment,and that in the observation group was lower than that in the control group(P<0.05);there was no significant difference in glycosylated hemoglobin(HbA1c)level between the two groups(P>0.05).After treatment,visual analogue scale(VAS)scores and Michigan neuropathy screening instruments(MNSI)scores of both groups were lower than those before treatment,and those in observation group were lower than those in control group(P<0.05).After treatment,the sensory nerve conduction velocity(SNCV)and motor nerve conduction velocity(MNCV)of median nerve and common peroneal nerve in both groups were higher than those before treatment,and those in the observation group were higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The effect of traditional Chinese medicine foot bath combined with auricular point pressi
关 键 词:痛性糖尿病周围神经病变 中药足浴 耳穴压豆
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...