细胞外囊泡在静脉血栓栓塞症中的作用  

The role of extracellular vesicles in venous thromboembolism

作　　者：张继伟[1] 李钦丽 Zhang Jiwei;Li Qinli(Department of Pathology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022;Department of Clinical Laboratory,Dongxihu District People’s Hospital,Wuhan 430040)

机构地区：[1]华中科技大学同济医学院附属协和医院病理科,武汉430022 [2]武汉市东西湖区人民医院检验科,武汉430040

出　　处：《中国组织化学与细胞化学杂志》2025年第1期86-91,共6页Chinese Journal of Histochemistry and Cytochemistry

基　　金：华中科技大学同济医学院附属协和医院自由创新预研基金(2022xhyn028)。

摘　　要：静脉血栓栓塞症(venous thromboembolism,VTE)是一种常见的血管疾病,其与心脏病、中风等疾病一样,对人类健康构成严重的威胁。细胞外囊泡(extracellular vesicles,EVs)是一种小型的囊泡结构,由细胞膜包裹的细胞外囊泡在细胞间传递信息和分子,其在许多生理和病理过程中起着重要的调节作用。近年来,研究人员对EVs在VTE中的作用进行了广泛的研究,本文将对其研究进展进行综述,以更全面、更详细地了解EVs在VTE中的作用。Venous thromboembolism(VTE)is a common vascular disease that,like heart disease and stroke,poses a serious threat to human health.Extracellular vesicles(EVs)are small vesicular structures enclosed by the cell membrane.They mediate the transfer of information and molecules between cells and play important regulatory roles in a variety of physiological and pathological processes.In recent years,researchers have conducted extensive studies on the role of EVs in VTE.This article aims to review the research progress in this field to gain a more comprehensive and in-depth understanding of the mechanisms by which EVs function in VTE.

关 键 词：细胞外囊泡 静脉血栓栓塞症 生物标志物 

分 类 号：R543[医药卫生—心血管疾病]