Functional genomics dissection of the nodulation autoregulation pathway(AON)in soybean(Glycine max)  

作　　者：Peter M.Gresshoff Chao Su Huanan Su April Hastwell Yanyan Cha Mengbai Zhang Estelle B.Grundy Xitong Chu Brett J.Ferguson Xia Li 

机构地区：[1]Integrative Legume Research Group,School of Agriculture and Food Sustainability,The University of Queensland,St Lucia,Brisbane,Queensland 4072,Australia 2.National Key Laboratory of Crop Genetic Improvement,College of Plant Science and Technology,Huazhong Agricultural University,Hongshan Laboratory,Wuhan,Hubei 430070,China

出　　处：《Journal of Integrative Plant Biology》2025年第3期762-772,共11页植物学报(英文版)

基　　金：supported by the National Natural Science Foundation of China grants(32441047;32330078);the Australian Research Council Discovery Project(DP190102996)。

摘　　要：The combination of mutation-based genetics and functional genomics has allowed a detailed dissection of the nodulation-induction and autoregulation of nodulation(AON)pathways of soybean.Applicable to all legumes,nodulation is induced by Rhizobium/Bradyrhizobium-produced lipopolysaccharides(Nod factors),perceived by Nod factor receptors(NFR1/NFR5 dimers),leading to cortical and pericycle cell divisions.These induce the production of CLAVATA3-like(CLE)peptides,which travel in the xylem to the shoot,where they are perceived by a receptor complex including a leucine-rich repeat(LRR)receptor kinase,encoded by Gm NARK,Lj HAR1,Mt SUNN and closely related receptors in other legumes like Phaseolus vulgaris(common bean),Pisum sativum(pea),and Glycine soja.The activated receptor complex negatively regulates by phosphorylation of the constitutive synthesis of mi R2111 in the shoot.This is normally is translocated via the phloem to the entire plant body,initiating suppression of a rootexpressed Kelch repeat-containing F-box protein“Too Much Love(TML),”which in turn suppresses the nodule initiation cascade.Nodulation is therefore permitted during a developmental window between the induction and progress of the nodulation/cell division/infection cascade during the first few days after inoculation and the functional“readiness”of the AON cascade,delayed by the root-shoot-root loop.Loss-of-function mutations in Gm NARK and Lj TML result in excessive nodulation(supernodulation/hypernodulation/supernummary nodulation)as well as localized tolerance to externally applied nitrate.Recent analyses have indicated an interaction of the AON with lateral root formation as well as with the autoregulation of mycorrhization(AOM).Further details of the parallel functions of key points in this regulatory loop remain to be elucidated.

关 键 词：autoregulation of nodulation legumes SOYBEAN symbiotic nodulation 

分 类 号：S565.1[农业科学—作物学]