发热伴血小板减少综合征的流行病学与防控策略  

Epidemiology and prevention strategies of sever fever with thrombocytopenia syndrome

作　　者：郑小杰 杨鑫 方立群 刘玮 ZHENG Xiaojie;YANG Xin;FANG Liqun;LIU Wei(State Key Laboratory of Pathogen and Biosecurity,Academy of Military Medical Sciences,Beijing 100071,China)

机构地区：[1]军事医学研究院,病原微生物生物安全全国重点实验室,北京100071

出　　处：《中华疾病控制杂志》2025年第3期249-253,261,共6页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(82330103)。

摘　　要：发热伴血小板减少综合征(sever fever with thrombocytopenia syndrome,SFTS)是2009年在我国首次发现的新发蜱媒传染病,由发热伴血小板减少综合征病毒(severe fever with thrombocytopenia syndrome virus,SFTSV)(又称大别班达病毒)感染引起,该病的主要临床表现包括发热、血小板和白细胞减少等,病死率高达10%~30%。中国在全球范围内的SFTS病例数量最多,且发病率呈逐年上升趋势。SFTSV主要通过蜱虫叮咬传播,SFTS患者或SFTSV感染动物的血液和体液也具有传染性。目前尚无特效药和疫苗用于治疗或预防SFTS。因此,深入研究其流行病学特征、传播途径、高危人群及影响因素尤为重要。加快药物和疫苗的研发进程、强化监测体系、提高公众意识、完善防控措施对保障人民健康和公共安全具有重大意义。Severe fever with thrombocytopenia syndrome(SFTS)is a newly emerged tick-borne infectious disease first discovered in China in 2009,caused by the severe fever with thrombocytopenia syndrome virus(SFTSV),also known as Dabie bandavirus.The main clinical manifestations of this disease include fever,thrombocytopenia,and leukopenia,with a high mortality rate of 10%to 30%.China has reported the highest number of cases globally,and there has been an increase in the annual incidence rate.SFTSV is primarily transmitted through tick bites,and the blood and body fluids of patients or infected animals are also contagious.Currently,there are no specific drugs or vaccines available for the treatment or prevention of this disease.Therefore,it is crucial to conduct in-depth research on its epidemiological characteristics,transmission routes,high-risk populations,and influencing factors.The development of drugs and vaccines,the strengthening of surveillance systems,the increase of public awareness,and the improving of prevention and control measures are of great significance for people's health and public safety.

关 键 词：发热伴血小板减少综合征 流行病学 监测 防控策略 

分 类 号：R511[医药卫生—内科学] R181[医药卫生—临床医学]