中药多糖抗糖尿病作用机制及其发展前景  

Antidiabetic mechanism of polysaccharides in traditional Chinese medicine and its development prospect

作　　者：王天一 高陈佳 董晓范 李凌军[1] WANG Tianyi;GAO Chenjia;DONG Xiaofan;LI Lingjun(College of Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250000,China)

机构地区：[1]山东中医药大学药学院,山东济南250000

出　　处：《中草药》2025年第6期2184-2196,共13页Chinese Traditional and Herbal Drugs

摘　　要：中药多糖是中药的主要化学成分之一,其结构丰富、安全性高。近年来关于中药多糖的生物活性报道较多,展现了其广阔的开发前景。糖尿病是一类以高血糖为主要特征的代谢性疾病。据报道,中国是世界上糖尿病人口最多的国家,约占全球糖尿病患者总数的22%。通过对中药多糖治疗糖尿病的构效关系、作用机制及其发展前景进行综述,为中药多糖在糖尿病治疗领域的开发研究提供理论依据。Polysaccharides from traditional Chinese medicine(TCM)are one of the main chemical components of TCM,characterized by their rich structures and high safety profile.In recent years,there have been numerous reports on the biological activities of TCM polysaccharides,demonstrating their broad potential for development.Diabetes is a group of metabolic diseases primarily characterized by high blood glucose levels.It is reported that China has the largest number of people with diabetes in the world,accounting for approximately 22%of global total.By reviewing the structure-activity relationships,mechanisms of action,and development prospects of TCM polysaccharides in the treatment of diabetes,this article provides a theoretical basis for the development and research of TCM polysaccharides in the field of diabetes treatment.

关 键 词：中药多糖 可视化 糖尿病 化学修饰 制剂 

分 类 号：R285[医药卫生—中药学]