内脏手法调理术对胚胎再次移植妊娠结局的影响  

The impact of visceral manipulation on improving the outcomes of embryo re-implantation pregnancy

作　　者：李英杰 席朝垒 赵君利[1] LI Yingjie;XI Chaolei;ZHAO Junli(Reproductive Center,General Hospital of Ningxia Medical University,Yinchuan 750004,China;The First Clinical Medical School,Ningxia Medical University,Yinchuan 750004,China;Third People′s Hospital of Huai′an,Huai′an 223001,China)

机构地区：[1]宁夏医科大学总医院,宁夏银川750004 [2]宁夏医科大学第一临床医学院,宁夏银川750004 [3]江苏淮安市第三人民医院,江苏淮安223001

出　　处：《宁夏医学杂志》2025年第3期209-212,共4页Ningxia Medical Journal

基　　金：中国生殖医学基金项目(20150170)。

摘　　要：目的观察内脏手法调理术对体外受精(IVF)种植失败胚胎再次移植妊娠结局的影响。方法回顾性收集胚胎移植前接受内脏手法调理术的34例患者资料,将其中同一取卵周期再次胚胎移植的23例患者按照前次移植周期次数分为2组,鲜胚未孕再次冻胚移植的有11例(鲜胚-冻胚组),胚胎移植次数≥2次未孕再次冻胚移植的有12例(冻胚-冻胚组),采用前后自身对照研究比较内脏手法调理术前、术后移植周期助孕结局。结果所有接受治疗患者无任何不适,术后自述下腹温热感明显。34例患者内脏手法调理术前共移植63个周期,生化妊娠率为6.35%,异位妊娠率为1.59%,临床妊娠率为20.63%,早期流产率为38.46%,活产率为61.54%;内脏手法调理术后共34个周期,生化妊娠率为5.88%,临床妊娠率为47.06%,早期流产率为6.25%,活产率为93.75%。冻胚-冻胚组患者治疗后周期移植日内膜的形态较治疗前周期明显改善,周期临床妊娠率较治疗前提高50%(P<0.05)。治疗后周期临床妊娠率较治疗前周期提高54.54%(P<0.05)。结论内脏手法调理术无创、简单、安全,能显著改善同一取卵周期鲜胚、冻胚移植失败患者再次胚胎移植妊娠结局。Objective To observe the effect of visceral manipulation on pregnancy outcomes of patients with implantation failure in IVF.Methods A total of 34 patients who underwent visceral manipulation prior to embryo transfer.The 23 patients who underwent embryo transfer during the same oocyte retrieval cycle were divided into two groups based on the number of previous transfer cycles.11 cases of fresh embryo transfer without pregnancy followed by frozen embryo transfer(Fresh-Frozen group),and 12 cases of frozen embryo transfer after two or more unsuccessful embryo transfers(Frozen-Frozen group).A self-controlled study was conducted to evaluate the outcomes of assisted reproduction during the pre-and post-operative transfer cycles using visceral manipulation.Results All treated patients reported no discomfort,and they described a noticeable warmth sensation in the lower abdomen post-surgery.A total of 34 patients underwent a total of 63 embryo transfers prior to visceral manipulation,resulting in a biochemical pregnancy rate of 6.35%,an ectopic pregnancy rate of 1.59%,a clinical pregnancy rate of 20.63%,an early miscarriage rate of 38.46%,and a live birth rate of 61.54%.After the visceral manipulation,there were a total of 34 embryo transfer cycles,resulting in a biochemical pregnancy rate of 5.88%,a clinical pregnancy rate of 47.06%,an early miscarriage rate of 6.25%,and a live birth rate of 93.75%.The morphology of the endometrium in Frozen-Frozen group on the day of embryo transfer after treatment showed significant improvement compared to the cycles before treatment,with the clinical pregnancy rate increasing by 50%compared to before treatment,which was statistically significant(P<0.05).The clinical pregnancy rate after treatment increased by 54.54%compared to the cycles before treatment(P<0.05).Conclusion Visceral manipulation is non-invasive,simple,safe and significantly improves the outcome of subsequent embryo transfer in patients who experience failure after fresh or frozen embryo transfers during the same oocyte

关 键 词：种植失败 内脏手法调理术 自身对照 

分 类 号：R339.2[医药卫生—人体生理学]