复合眼霜改善眼周早期老化症状的评估研究  

Efficacy evaluation of a compound eye cream for early aging symptoms in the periorbital area

作　　者：叶迎 叶芳 魏晓岚 李亚男 Ying Ye;Fang Ye;Xiaolan Wei;Yanan Li(Research&Innovation Center,Proya Cosmetics Co.,Ltd.,Zhejiang,Hangzhou 310012,China)

机构地区：[1]珀莱雅化妆品股份有限公司研发创新中心,浙江杭州310012

出　　处：《日用化学工业(中英文)》2025年第4期487-494,共8页China Surfactant Detergent & Cosmetics

摘　　要：评估含薰衣草花提取物、二肽-4、抗坏血酸四异棕榈酸酯、齿叶乳香树脂提取物、葡糖基橙皮苷、生育酚烟酸酯、芽孢杆菌发酵产物和咖啡因的眼霜对改善眼周早期衰老症状的人体功效。31名有轻中度黑眼圈、眼周皱纹和眼袋的27~45岁中国女性参加了研究,在眼周涂抹眼霜,每天两次,持续4周。通过非侵入式仪器、皮肤科医生评估以及志愿者自我评估,对使用产品前后的眼周皮肤进行功效评价。结果显示,局部使用眼霜能提亮肤色、改善黑眼圈、眼袋和细纹。使用2周后,黑眼圈区域的黑色素指数、红斑指数、皮肤肤色,眼袋体积和眼周皱纹参数均有了明显的改善,并持续至4周后。皮肤科医生评估、志愿者自评与仪器客观数据具有良好的相关性和一致性。该研究介绍了一种基于仪器定量测量和主观评估的综合评价方法,用于评估黑眼圈和眼袋的改善情况,以期为开发眼周护肤配方提供有价值的思路。This study aimed to assess the human efficacy of an eye cream formulated with Lavandula angustifolia(lavender)flower extract,dipeptide-4,ascorbyl tetraisopalmitate,Boswellia serrata resin extract,glucosyl hesperidin,tocopheryl nicotinate,bacillus ferment and caffeine for treating early aging symptoms around the eyes.A total of 31 Chinese women aged 27 to 45 years with noticeable dark circles,periorbital wrinkles,and eye bags participated in the study.They applied the eye cream around the eyes twice daily for four weeks.Evaluation of periorbital skin before and after product usage was conducted through non-invasive instrumentation,dermatologist assessment,and subject self-assessment.The results show that partial use of eye cream can significantly brighten skin color,and improve dark circles,eye bags,and fine lines.After 2 weeks of use,there is a significant improvement in the melanin index,erythema index,skin color,eye bag volume,and periorbital wrinkle parameters,which continue to improve up to 4 weeks.It is worth noting that the subjective evaluations by dermatologists and volunteers show good correlation and consistency with the instrument data.This study presents a comprehensive evaluation method based on quantitative instrument measurements and subjective assessments,providing valuable insights for developing eye area skincare formulations.

关 键 词：眼周老化 眼袋 黑眼圈 细纹 仪器评估 

分 类 号：TQ658[化学工程—精细化工]