Stochastic thermodynamics for biological functions  

作　　者：Yuansheng Cao Shiling Liang 

机构地区：[1]Department of Physics,Tsinghua University,Beijing,China [2]Institute of Physics,School of Basic Sciences,École Polytechnique Fédérale de Lausanne(EPFL),Lausanne,Switzerland

出　　处：《Quantitative Biology》2025年第1期29-47,共19页定量生物学(英文版)

基　　金：National Natural Science Foundation of China,Grant/Award Number:12374213;Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung,Grant/Award Number:200020_178763。

摘　　要：Living systems operate within physical constraints imposed by nonequilibrium thermodynamics.This review explores recent advancements in applying these principles to understand the fundamental limits of biological functions.We introduce the framework of stochastic thermodynamics and its recent developments,followed by its application to various biological systems.We emphasize the interconnectedness of kinetics and energetics within this framework,focusing on how network topology,kinetics,and energetics influence functions in thermodynamically consistent models.We discuss examples in the areas of molecular machine,error correction,biological sensing,and collective behaviors.This review aims to bridge physics and biology by fostering a quantitative understanding of biological functions.

关 键 词：biological functions physical constraints stochastic thermodynamics 

分 类 号：O414.1[理学—理论物理]