心血管-肾脏-代谢综合征视角下动脉粥样硬化性心血管疾病的现状与管理策略  

Current Status and Management Strategies of Atherosclerotic Cardiovascular Disease from The Perspective of Cardio-Renal-Metabolic Syndrome

作　　者：殷钰喆 李喆[1] 吴永健[1] YIN Yuzhe;LI Zhe;WU Yongjian(Coronary Heart Disease Center,Fuwai Hospital,National Center for Cardiovascular Disease,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100037,China)

机构地区：[1]中国医学科学院,北京协和医学院,国家心血管病中心,阜外医院冠心病中心,北京100037

出　　处：《心血管病学进展》2025年第4期289-293,共5页Advances in Cardiovascular Diseases

基　　金：中央高水平医院临床科研业务费资助(零余额2023-GSP-GG-38)。

摘　　要：心血管-肾脏-代谢(CKM)综合征是由肥胖、糖尿病、慢性肾脏病和心血管疾病之间的病理生理相互作用导致的全身性疾病。动脉粥样硬化性心血管疾病(ASCVD)作为最重要的心血管疾病之一,对其的预防和管理是改善心血管疾病预后的核心。随着CKM综合征概念的提出,结合心血管系统以外其他系统共同管理以预防和治疗ASCVD得到越来越多的关注。现以CKM综合征中ASCVD为切入点,深入探讨在CKM综合征背景下ASCVD的流行病学现状、病理生理机制及治疗管理策略。建议通过多学科共同诊疗开展对ASCVD的综合管理,并建立系统的全年龄段筛查,以确立针对这一人群更早期、有效的管理计划。Cardiovascular-kidney-metabolic(CKM)syndrome is a systemic disease caused by the pathophysiological interactions among obesity,diabetes,chronic kidney disease and cardiovascular disease.Atherosclerotic cardiovascular disease(ASCVD),as one of the most important cardiovascular diseases,its prevention and management are the core to improve the prognosis of cardiovascular diseases.With the introduction of the concept of CKM syndrome,more and more attention has been paid to ASCVD by combining the management of other systems outside the cardiovascular system.This review takes ASCVD in CKM syndrome as the entry point to deeply discuss the epidemiological status,pathophysiological mechanism and treatment management strategies of ASCVD in the context of CKM syndrome.It is recommended to carry out comprehensive management of ASCVD through multidisciplinary diagnosis and treatment and establish a systematic screening for all ages to establish an earlier and more effective management plan for this population.

关 键 词：心血管-肾脏-代谢综合征 动脉粥样硬化性心血管疾病 2型糖尿病 慢性肾脏病 

分 类 号：R54[医药卫生—心血管疾病]