450例纤维肌痛症患者用药分析  

Analysis of Drug Use in 450 Patients with Fibromyalgia

作　　者：龙梅娟 李延婷 王怡丹 武诗雅 李梓豪 李阳 孙雨若 焦娟[1] LONG Mei-juan;LI Yan-ting;WANG Yi-dan;WU Shi-ya;LI Zi-hao;LI Yang;SUN Yu-ruo;JIAO Juan(Rheumatology Department,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053)

机构地区：[1]中国中医科学院广安门医院风湿病科,北京100053

出　　处：《中国中西医结合杂志》2025年第3期290-296,共7页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：中国中医科学院创新工程项目(No.CI2021A01505)。

摘　　要：目的通过问卷调查了解目前纤维肌痛症的治疗现状。方法采用横断面研究设计,调查患者既往治疗情况,随后由患者自行填写自评问卷或量表,包括普遍疼痛指数(WPI)评分、症状严重性量表(SSS)评分、疼痛视觉模拟评分法(VAS)评分、修订版纤维肌痛影响问卷(FIQR)评分。结果共有450例患者参与调查,平均处于轻度疾病整体影响水平[平均FIQR评分为(40.5±17.3)分]和中等疼痛水平[平均疼痛VAS评分为(5.8±1.9)分],79.1%(356例)的患者压痛点个数11个。其中曾接受过治疗的患者为283例(62.9%),包括西药治疗123例(27.3%)和中医治疗213例(47.3%),共计接受治疗509例次。在509例次治疗中,西药治疗共211例次(41.5%),其中非甾体抗炎药59例次(11.6%)应用最为普遍,其次为抗抑郁药47例次(9.2%)和镇静催眠药30例次(5.9%);中医治疗共298例次(58.5%),其中常用的中医疗法依次为中药汤剂136例次(26.7%)、针灸62例次(12.2%)和中成药46例次(9.0%)。结论研究中仅不足三分之二的纤维肌痛症患者接受过治疗,药物治疗的选择尚缺少循证依据,非药物治疗明显不足。Objective To understand the current status of fibromyalgia treatment by a questionnaire survey.Methods A cross-sectional study design was used to investigate the patients'previous treatment status,and then the patients filled in self-assessment questionnaires or scales,including the Widespread Pain Index(WPI)score,the Symptom Severity Scale(SSS)score,the pain Visual Analogue Scale(VAS)score,and the Revised Fibromyalgia Impact Questionnaire(FIQR)score.Results A total of 450 patients participated in the survey,with an average overall mild disease impact level(mean FIQR score of 40.5±17.3 points)and moderate pain level(mean pain VAS score of 5.8±1.9 points),and 79.1%(356 cases)of patients had 11 tender point count.Among them,283 patients(62.9%)had received treatment,including 123 patients(27.3%)treated with Western medicine and 213 patients(47.3%)treated with Chinese medicine,and a total of 509 treatments were received.Among the 509 treatments,Western medicine treatment accounted for 211 instances(41.5%),with nonsteroidal anti-inflammatory drugs being the most commonly used in 59 instances(11.6%),followed by 47 treatments(9.2%)of anti-depressants and 30 treatments(5.9%)of sedatives and hypnotics.There were 298 treatments(58.5%)of Chinese medicine treatments,of which the commonly used Chinese medicine therapies were 136 treatment(26.7%)of Chinese herbal decoctions,62 treatments(12.2%)of acupuncture and moxibustion,and 46 treatments(9.0%)of Chinese patent medicines.Conclusion Currently,less than two-thirds of fibromyalgia patients in this study have received treatment,with a lack of evidence-based support for the choice of pharmacological therapy and a significant deficiency in non-pharmacological treatment options.

关 键 词：纤维肌痛 药物治疗 非药物治疗 中医 横断面研究 问卷调查 

分 类 号：R685[医药卫生—骨科学]