2021—2023年南京某医院肺炎克雷伯菌感染的临床分布及耐药性分析  

Analysis of Clinical Distribution and Drug Resistance of Klebsiella Pneu⁃moniae Infections in Hospital in Nanjing from 2021 to 2023

作　　者：孙士佳 杨侠宇 杨倩倩 雍定坤 徐静 余月嫚 SUN Shijia;YANG Xiayu;YANG Qianqian;YONG Dingkun;XU Jing;YU Yueman(Department of Clinical Laboratory,Nanjing Meishan Hospital,Nanjing 210039,Jiangsu,China)

机构地区：[1]南京梅山医院检验科,江苏南京210039

出　　处：《中国卫生产业》2025年第1期217-220,225,共5页China Health Industry

摘　　要：目的分析南京某医院2021—2023年肺炎克雷伯菌的分布情况及其耐药性。方法选取2021年1月—2023年12月南京梅山医院分离的790株肺炎克雷伯菌,分析肺炎克雷伯菌不同年份的分离情况、标本类型分布、科室分布情况及耐药性。结果2021—2023年共检出790株肺炎克雷伯菌,2021年的分离率为20.42%(195/955),2022年的分离率为22.51%(305/1355),2023年分离率为19.55%(290/1483)。肺炎克雷伯菌主要分布于ICU、呼吸科、普外科、神经内科,痰液是最常见的标本类型。肺炎克雷伯菌对抗菌药物的耐药性在非ICU中普遍较低,而在ICU中则明显增加。结论肺炎克雷伯菌的耐药率较高,多个部门之间需紧密合作,密切关注其耐药情况,精准用药以降低抗菌药物耐药率和多重耐药菌发生率。Objective To analyze the distribution of Klebsiella pneumoniae and its drug resistance in a hospital in Nanjing from 2021 to 2023.Methods 790 strains of klebsiella pneumoniae isolated from January 2021 to December 2023 in Nanjing Meishan Hospital,were selected to analyze the isolation of Klebsiella pneumoniae in different years,the distribution of specimen types,the distribution of departments and drug resistance.Results A total of 790 Klebsi‐ella pneumoniae strains were detected from 2021 to 2023,with isolation rates of 20.42%(195/955)in 2021,22.51%(305/1355)in 2022,and 19.55%(290/1483)in 2023.Klebsiella pneumoniae was mainly found in ICU,respiratory,general surgery,and neurology departments,and sputum was the most common specimen type.Resistance of Klebsi‐ella pneumoniae to antimicrobials was generally low in non-ICUs and increased significantly in ICU.Conclusion Klebsiella pneumoniae has a high rate of drug resistance,and close collaboration between multiple departments is needed to closely monitor its drug resistance and administer drugs precisely to reduce the rate of antimicrobial resis‐tance and the incidence of multidrug-resistant bacteria.

关 键 词：肺炎克雷伯菌 临床分布 耐药性 

分 类 号：R19[医药卫生—卫生事业管理]