评估手术入路(经肛门与经腹部)对早期直肠癌肿瘤预后和生活质量的影响:一项评估R0切除率和肠功能结局的回顾性队列研究  

To Evaluate the Effect of Surgical Approach(Transanal and Transabdominal)on the Prognosis and Quality of Life of Patients with Early Rectal Cancer:A Retrospective Cohort Study to Evaluate R0 Resection Rate and Bowel Function Outcome

作　　者：郭海龙 韩宇田 曲巍 白雪峰 吴昊 刘晓明 王钟焰 GUO Hai-long;HAN Yu-tian;QU Wei;BAI Xue-feng;WU Hao;LIU Xiao-ming;WANG Zhong-yan(Department of Proctology,The Third Affiliated Hospital of Qiqihar Medical College,Qiqihar Heilongjiang 161000,China;Department of General Surgery,The Third Affiliated Hospital of Qiqihar Medical College,Qiqihar Heilongjiang 161000,China)

机构地区：[1]齐齐哈尔医学院附属第三医院肛肠科,黑龙江齐齐哈尔161000 [2]齐齐哈尔医学院附属第三医院普外三科,黑龙江齐齐哈尔161000

出　　处：《中华养生保健》2025年第5期171-174,共4页CHINESE HEALTH CARE

基　　金：齐齐哈尔市科技计划联合引导项目(LSFGG-2024008)。

摘　　要：目的探究不同手术入路对早期直肠癌肿瘤患者预后和生活质量的影响。方法选取2021年1月—2023年6月齐齐哈尔医学院附属第三医院收治的60例直肠癌患者作为研究对象,所有患者均择期行直肠癌根治术治疗。根据手术入路不同将其分对照组(腹部入路,n=30)和观察组(肛门入路,n=30),比较两组肿瘤完全(R0)切除率、肠功能结局和生活质量。结果观察组R0切除率显著高于对照组,差异有统计学意义(P<0.05);手术前,两组胃肠道症状评定量表(GSRS)评分比较,差异无统计学意义(P>0.05),手术后1周,观察组GSRS评分显著低于对照组,差异有统计学意义(P<0.05);手术前,两组Spitzer生活质量(SQLI)评分比较,差异无统计学意义(P>0.05),手术后2年,观察组SQLI评分显著高于对照组,差异有统计学意义(P<0.05)。结论经肛门入路的直肠癌切除手术较腹部入路更优,R0切除率更高,术后患者肠功能恢复良好,可有效提升患者生存率和生活质量。Objective To investigate the effect of different surgical approaches on prognosis and quality of life in early stage rectal cancer tumors.Methods A retrospective analysis was performed on 60 patients with rectal cancer admitted to the Third Affiliated Hospital of Qiqihar Medical College from 2021.1 to 2023.6.All patients underwent elective radical resection of rectal cancer.According to different surgical approaches,they were divided into control group(abdominal approach,n=30)and observation group(anal approach,n=30).The complete(R0)resection rate,intestinal function outcome and quality of life were compared between the two groups.Results The R0 resection rate in the observation group was significantly higher than that in the control group(93.33%vs 73.33%)(P<0.05);there was no statistically significant difference in the Gastrointestinal Symptom Rating Scale(GSRS)scores between the two groups before surgery(P>0.05),and one week after surgery,the GSRS scores of the observation group were significantly lower than those of the control group(P<0.05);there was no statistically significant difference in the Spitzer Quality of Life Index(SQLI)scores between the two groups before surgery(P>0.05),and two years after surgery,the SQLI scores of the observation group were significantly higher than those of the control group(P<0.05).Conclusion The rectal cancer resection through the anal approach is better than the abdominal approach,and the R0 resection rate is 93.33%.The postoperative intestinal function of the patients recovered well,which can effectively improve the survival rate and quality of life of the patients.intestinal function.

关 键 词：早期直肠癌 肿瘤 切除率 肠功能 

分 类 号：R657.1[医药卫生—外科学]