D-二聚体在内科急诊中疾病分布及临床意义分析  

Analysis of the distribution status and clinical significance of D-dimer disease

作　　者：刘忠芬 董晓青 宋颖 Liu Zhongfen;Dong Xiaoqing;Song Ying(Emergency Department,Zhangqiu District People's Hospital,Jinan,Shandong,250200,China;Medical Record Department,Zhangqiu District People's Hospital,Jinan,Shandong,250200,China)

机构地区：[1]济南市章丘区人民医院急诊科,山东济南250200 [2]济南市章丘区人民医院病案科,山东济南250200

出　　处：《西藏医药》2025年第2期24-25,共2页Tibetan Medicine

基　　金：D二聚体疾病分布现状及临床意义分析,项目编号:202413。

摘　　要：目的探究D-二聚体在内科急诊疾病患者分布及临床意义。方法收集2021年1月1日~2022年1月1日我院急诊收治的内科疾病患者3991例。按不同疾病分为脑梗组(1812例)、心梗组(192例)、心衰组(667例)、肺癌组(359例)、胰腺炎组(204例)、急性肺炎组(202例)、急性上消化道出血组(190例)、泌尿系感染组(109例)、肝脓肿组(78例)、脑出血组(56例)、类风湿关节炎组(52例)、结肠癌组(42例)。通过胶乳免疫比浊法测定D-二聚体水平,分析D-二聚体升高与疾病的并发症及预后的临床意义。结果D-二聚体升高:脑梗、心梗组低于其他组,感染性疾病组高于其他组,其他组间也存在差异;预后:脑梗组死亡率最低,心衰组和感染性组最高。结论内科急诊住院患者中,DDM升高提示,疾病本身有严重并发症,死亡率高。Objective To explore the distribution and clinical significance of D-dimer in patients with internal medicine emergencies.Method A total of 3991 patients with internal medicine diseases who were admitted to the emergency department of our hospital from January 1,2021,to January 1,2022,were collected.The patients were divided into different disease groups,including cerebral infarction group(1812 cases),myocardial infarction group(192 cases),heart failure group(667 cases),lung cancer group(359 cases),pancreatitis group(204 cases),acute pneumonia group(202 cases),acute upper gastrointestinal bleeding group(190 cases),urinary tract infection group(109 cases),liver abscess group(78 cases),cerebral hemorrhage group(56 cases),rheumatoid arthritis group(52 cases),and colorectal cancer group(42 cases).The levels of D-dimer were determined by latex immunoagglutination turbidimetric assay,and the clinical significance of D-dimer elevation in terms of complications and prognosis was analyzed.Results D-dimer elevation:the cerebral infarction and myocardial infarction groups had lower levels than other groups,and the infection disease groups had higher levels than other groups;there were also differences among other groups;prognosis:the mortality rate of the cerebral infarction group was the lowest,and the heart failure and infection groups had the highest mortality rates.Conclusion In patients with internal medicine emergencies admitted to the emergency department,an increase in D-dimer levels indicates that the disease itself has serious complications and a high mortality rate.

关 键 词：D-二聚体 内科疾病 预后 

分 类 号：R459.7[医药卫生—急诊医学]