百合的炮制历史沿革、化学成分及药理作用研究进展  

Research progress on processing history evolution,chemical constituents and pharmacological action of Lily Bulbus

作　　者：郭静英 王楷睿 龚文慧 辛力 邓亚羚 谌瑞林[1,2] 钟凌云 杨明[1,3] 张金莲[1] GUO Jingying;WANG Kairui;GONG Wenhui;XIN Li;DENG Yaling;CHEN Ruilin;ZHONG Lingyun;YANG Ming;ZHANG Jinlian(College of Pharmacy,Jiangxi University of Chinese Medicine,Nanchang 330004,China;Jiangxi Jiangzhong Traditional Chinese Medicine Pieces Co.,Ltd,Jiujiang 332300,China;Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,College of Pharmacy,Jiangxi University of Chinese Medicine,Nanchang 330004,China)

机构地区：[1]江西中医药大学药学院中药炮制教研室,南昌330004 [2]江西江中中药饮片有限公司,九江332300 [3]江西中医药大学药学院现代中药制剂教育部重点实验室,南昌330004

出　　处：《中华中医药杂志》2025年第3期1327-1336,共10页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家重点研发计划(No.2018YFC1707206);国家级大学生创新创业训练计划项目(No.D202106111038584970,No.202210412288);省中医药标委会标准化项目(No.2021B01,No.2021B02);江西中医药大学首批校级创新团队项目(No.CXTD22003);江西中医药大学校级研究生创新专项(No.JZYC22S57)。

摘　　要：百合始载于《神农本草经》,被列为中品,有养阴润肺、清心安神之效。作为一种药食两用中药,百合的炮制历史悠久,始于汉代,炮制方法多样,除沿用至今的蜜炙以外,古代还出现了炒制、蒸制等多种炮制方法。目前已经从百合中分离鉴定得到皂苷类、黄酮类、酚酸甘油类、生物碱类、多糖类及其他多种化合物。现代研究表明,百合具有止咳祛痰、抗抑郁、镇静、降血糖、抗肿瘤、抗氧化等药理作用。笔者查阅整理古代本草、现代药典、地方中药饮片炮制规范及相关研究文献,对百合的炮制历史沿革、化学成分及药理作用系统化地开展综述,以期为百合的特色饮片炮制及现代研究提供参考。Lily Bulbus was originally recorded in the Sheng Nong's Herbal classic,and was listed as a medium grade Chinese medicine.It has the effects of nourishing yin,moistening the lung,clearing the heart,and calming the nerves.As a Chinese medicine for both medicine and food,Lily Bulbus has a long history of processing,dating back to the Han dynasty.There are various processing methods.In addition to honey roasting,there were also various processing methods such as stirfrying and steaming in ancient times.Up to now,saponins,flavonoids,phenolic glycerols,alkaloids,polysaccharides,and many other compounds have been isolated and identified from Lily Bulbus.Modern researches have shown that Lily Bulbus has pharmacological effects such as cough relieving and expectorant,anti-inflammatory,antidepressant,sedative,hypoglycemic,antitumor and antioxidant.Review and sort out ancient herbs,modern pharmacopoeia,processing specifications of local traditional Chinese medicine slices,and relevant research literature,and systematically summarize the processing history,chemical components,and pharmacological effects of Lily Bulbus,with a view to providing references for the processing and modern research of Lily Bulbuscharacteristic decoction slice.

关 键 词：百合 炮制历史沿革 化学成分 药理作用 

分 类 号：R283.1[医药卫生—中药学]