基于“肺主皮毛”理论探讨过敏性哮喘-特应性皮炎共病  

Discussion on allergic asthma-atopic dermatitis comorbidity based on theory of ‘lung dominating skin and hair'

作　　者：张慧婷 李友林[2] 左先波 李春雷[2] 梁瑞[1] 阎玥[2] ZHANG Huiting;LI Youlin;ZUO Xianbo;LI Chunlei;LIANG Rui;YAN Yue(Beijing University of Chinese Medicine,Beijing 100029,China;Department of Integrated TCM and Western Medicine for Pulmonary Diseases,China-Japan Friendship Hospital,Beijing 100029,China;Department of Big Data Research,China-Japan Friendship Hospital,Beijing 100029,China)

机构地区：[1]北京中医药大学,北京100029 [2]中日友好医院中西医结合肺病科,北京100029 [3]中日友好医院大数据研究部,北京100029

出　　处：《中华中医药杂志》2025年第3期1448-1451,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：中日友好医院高水平医院临床项目业务费专项临床研究项目(No.2023-NHLHCRF-YYPPLC-ZR-07);国家自然科学基金青年科学基金项目(No.81302943)。

摘　　要：过敏性哮喘-特应性皮炎(AA-AD)为临床常见特应性共病疾患,研究数据表明,近20%特应性皮炎(AD)患者同时罹患哮喘。目前AD与过敏性哮喘(AA)的全球发病率仍不断增长,治疗效果不佳,易反复发作。因此,如何减少药物不良反应、缓解症状及减轻疾病经济负担是目前函待解决的科学问题。文章基于“肺主皮毛”中医理论,提出“肺皮共病”疾病观点,通过研究AA-AD共病的临床表现及发病机制,探究中医药潜在干预靶点,内调理脏腑功能,外护肌表屏障,实现肺皮同调防治过敏性疾病。Allergic asthma(AA)and atopic dermatitis(AD)are common atopic comorbidities.Research data indicate that nearly 20%of patients with AD also suffer from asthma.Currently,the global incidence of AD and AA continues to rise,with neither condition having a fully satisfactory therapy.These two allergic diseases are prone to relapse,resulting in a significant economic burden.Therefore,reducing adverse drug reactions and alleviating symptoms are urgent concerns.Based on the traditional Chinese medicine(TCM)theory of ‘lung dominating skin and hair',we propose the concept of ‘lung and skinhair comorbidity'.By studying the clinical manifestations and pathogenesis of AA-AD comorbidity,to explore potential TCM intervention targets.Our goal is to regulate the functions of the viscera,strengthen the skin and hair protection barrier,and promote the prevention and treatment of allergic diseases by modulating the functions of the lung and skin-hair.

关 键 词：过敏性哮喘 特应性皮炎 肺皮共病 特应性进程 肺主皮毛 

分 类 号：R256.12[医药卫生—中医内科学]