关注环境内分泌干扰物的膳食暴露风险,保护易感人群健康  

Concerns over dietary exposure risks of environmental endocrine disruptors and protection for vulnerablepopulations

作　　者：高宇[1] 田英[1,2,3] GAO Yu;TIAN Ying(School of Public Health,Shanghai JiaoTong University School of Medicine,Shanghai 200025,China;MOE-Shanghai Key Laboratory of Children's Environmental Health,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China;State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants,Shanghai Jiao Tong University,Shanghai 200233,China)

机构地区：[1]上海交通大学医学院公共卫生学院,上海200025 [2]上海交通大学医学院附属新华医院环境与儿童健康教育部和上海市重点实验室,上海200092 [3]上海交通大学国家环境保护新型污染物环境健康影响评价重点实验室,上海200233

出　　处：《环境与职业医学》2025年第1期1-5,共5页Journal of Environmental and Occupational Medicine

基　　金：上海市科委自然科学基金项目(22ZR1435600);上海市加强公共卫生体系建设三年行动计划项目(2023-2025年)(GWVI-4、GWVI-11.1-41)。

摘　　要：环境内分泌干扰物(EDCs)是一类具有干扰机体内源性激素特点的外源化学物,可通过膳食、空气、灰尘等多种途径进入人体,进而对人群健康产生不良影响。其中,膳食是全氟化合物、多种农药、重金属和增塑剂等EDCs的重要暴露来源。亟待了解目前我国易感人群的环境内分泌干扰物的膳食暴露风险以及在此暴露水平下易感人群是否存在健康风险。近年来膳食暴露评估及其健康风险评估技术发展迅速,本文针对EDCs相关膳食暴露风险,对其目前的研究进展及未来展望进行综述。Endocrine disrupting chemicals(EDCs)are exogenous chemicals that interfere with human endogenous hormones.People can be exposed to EDCs through various routes,including diet,air,and dust,which increases the risk of adverse health outcomes.Among these routes,dietary exposure is themain source of EDCs,including per-and polyfluoroalkyl substances(PFAS),multiple pesticides,heavy metals,and phthalates.It is urgent to understand the dietary exposure risks of EDCs among susceptible populations in China,and to evaluate whether there are health risks for susceptible populations at current exposure levels.Rapid development in technologies of dietary exposure assessment and health risk assessment have been noted in recent years.This paper reviewed the current research progress and future prospects regarding the dietary exposure risks associated with EDCs.

关 键 词：环境内分泌干扰物 膳食暴露评估 易感人群 健康风险 

分 类 号：R12[医药卫生—环境卫生学]