组织工程学在输尿管修复中的应用研究进展  

Progress in the application of tissue engineering in ureteral repair

作　　者：黄义舜 杜毅聪 杨昆霖 李学松[1] HUANG Yishun;DU Yicong;YANG Kunlin;LI Xuesong(Department of Urology,Peking University First Hospital,Institute of Urology,Peking University,Beijing,100034,China)

机构地区：[1]北京大学第一医院泌尿外科北京大学泌尿外科研究所,北京100034

出　　处：《临床泌尿外科杂志》2025年第3期230-237,共8页Journal of Clinical Urology

基　　金：中央高水平医院临床科研业务费资助(北京大学第一医院青年临床研究专项)(No:2023YC16)。

摘　　要：用于输尿管修复的传统手术技术已有一定瓶颈,组织工程学在其中可能发挥巨大潜力。尽管还未踏足临床试验,针对组织工程输尿管的材料与细胞的许多研究已展现出令人欣喜的成果,但同时也面临着如支架材料免疫反应及长期效果不确定性、种子细胞的增殖分化难题等诸多挑战,需要长足的发展。本文就组织工程学在输尿管修复中的应用进展做一综述。Traditional surgical techniques for ureteral repair have certain bottlenecks,in which tissue engineering may play a great potential.Although yet to be tested clinically,numerous studies on materials and cells for tissue-engineered ureters have demonstrated promising results.However,they also face considerable challenges,such as the uncertainty of immune responses and long-term effects of scaffold materials,as well as the difficulties in the proliferation and differentiation of seed cells,necessitating further development.This article provides a critical review of the advancements in the application of tissue engineering for ureteral repair.

关 键 词：组织工程学 输尿管修复 干细胞 支架 

分 类 号：R693[医药卫生—泌尿科学]