基于肝心和合理论辨治动脉粥样硬化  

Differentiation and Treatment of Atherosclerosis Based on the Theory of Harmony between Liver and Heart

作　　者：陆玉雯 吴江岚 刘映志 柳岳 陈伶利[1,3] 李杰[1,2,4] LU Yuwen;WU Jianglan;LIU Yingzhi;LIU Yue;CHEN Lingli;LI Jie(Hunan University of Chinese Medicine,Changsha 410208,China;Provincial Key Laboratory of TCM Diagnostics,Hunan University of Chinese Medicine,Changsha 410208,China;Hunan Provincial Key Laboratory of Pathogenic Biology Based on Integrated Chinese and Western Medicine,Hunan University of Chinese Medicine,Changsha 410208,China;National Key Laboratory Cultivation Base of Chinese Medicinal Powder&Innovative Medicinal Jointly Established by Province and Ministry,Changsha 410208,China)

机构地区：[1]湖南中医药大学,湖南省长沙市410208 [2]湖南中医药大学中医诊断学湖南省重点实验室,湖南省长沙市410208 [3]湖南中医药大学中西医结合病原微生物学湖南省重点实验室,湖南省长沙市410208 [4]湖南省中药粉体与创新药物省部共建国家重点实验室培育基地,湖南省长沙市410208

出　　处：《实用心脑肺血管病杂志》2025年第6期88-91,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：国家自然科学基金资助项目(81874375);湖南省自然科学基金资助项目(2023JJ30452);湖南省中医药科研重点课题(C2023002);湖南中医药大学研究生创新课题(2024CX150,2024CX151,2024CX152);湖南省普通高等学校科技创新团队支持项目。

摘　　要：动脉粥样硬化(AS)是一种慢性脂质代谢障碍诱发的动脉内膜炎症性疾病,其病因与脂质代谢紊乱密切相关。本文基于中医肝心和合理论将AS的病因病机分为肝郁心阻起病始、肝心失司痰瘀增、肝心失合瘀毒变三个阶段,并提出分期治疗方案,如AS早期治疗以肝心同调、疏郁通脉为主,中期治疗强调调肝养心、豁痰宣痹,晚期治疗注重保心养肝、补虚固本,这体现肝心同治理念,此策略有望防治AS。Atherosclerosis(AS)is an inflammatory disease of the endarterium induced by chronic lipid metabolism disorders,its etiology is closely related to lipid metabolism disorders.Based on the theory of harmony between liver and heart in traditional Chinese medicine,this article divides the etiology and pathogenesis of AS into three stages:liver-stagnation and heartstagnation lead to the onset of disease,liver-heart disorder leads to increased phlegm and blood stasis,liver-heart disorder leads to the changing of stasis and toxin,and puts forward staged treatment program,which of early stage of AS was mainly regulating the liver and heart,dredging depression and clearing the veins;which of middle stage of AS was mainly regulating the liver and nourishing the heart,expelling phlegm and propagating paralysis;which of the late stage of AS was mainly preserving the heart and nourishing the liver,replenishing the deficiency and consolidating the foundation.This reflects the function of"treating both liver and heart".This strategy is expected to treat and prevent AS.

关 键 词：动脉粥样硬化 脂质代谢 肝心和合理论 综述 

分 类 号：R543.5[医药卫生—心血管疾病]