光照干预时刻对生物节律的影响研究  

Research on the Effect of Time of Light Intervention on Biological Rhythm

作　　者：李敬强 张焕晰 张雪萌 LI Jingqiang;ZHANG Huanxi;ZHANG Xuemeng(College of Safety Science and Engineering,Civil Aviation University of China,Tianjin 300300,China)

机构地区：[1]中国民航大学安全科学与工程学院,天津300300

出　　处：《综合运输》2025年第3期136-140,共5页China Transportation Review

基　　金：国家自然科学基金与民航联合基金(U1933122);民航安全能力建设项目(ASSA2023/20);中国民航大学波音基金项目(20221010238)。

摘　　要：民航运输人员昼夜节律紊乱会导致疲劳和认知能力下降等状况,从而影响安全运行。本研究通过光的非视觉效应通路对人体生物节律产生的影响,尝试探究短时光照调节人体生物节律的方法。为了探讨光照干预时刻对人体生物节律的影响,本研究从光的非视觉效应的本质出发,设计了光照干预实验。招募了51名健康大学生,分为五种不同光照时刻组进行2小时的光照,并在晨起6:00~8:00与晚间20:00~22:00,每半小时采集被试唾液样本,以评估不同光照时刻下光诱导的褪黑素抑制。研究结果表明,19:30~21:30光照组出现明显的褪黑素抑制,夜间光照对褪黑素抑制的效果越强。Circadian misalignment in civil aviation transportation personnel can lead to conditions such as fatigue and cognitive decline,affecting safety.This study investigates the method of adjusting biological rhythm by short-duration light intervention based on the non-visual effect of light on biological rhythm.To explore the effects of time of light intervention on biological rhythm,this study designed light intervention experiments.Fifty-one healthy college students were recruited and divided into five different controlled groups,taken light intervention for 2 h.Saliva samples were collected from the subjects every half hour from 6:00 to 8:00 in the morning and from 20:00 to 22:00 in the evening to assess melatonin suppression under different intervention times.The results of the study show that significant melatonin suppression occurred in the 19:30 to 21:30 group,and the stronger the effect of nighttime light on melatonin suppression.

关 键 词：非视觉效应 生物节律 光照时刻 光照干预 唾液褪黑素 

分 类 号：R85[医药卫生—航空、航天与航海医学]