帕罗西汀联合心理治疗对脑梗死后抑郁患者神经功能康复的影响  

The effects of paroxetine combined with psychotherapy on depression and neurological rehabilitation after erebral infarction

作　　者：赵小博 冉辉 马英 李扬帆 李芳英 ZHAO Xiaobo;RAN Hui;MA Ying;LI Yangfan;LI Fangying(The First People's Hospital of Huating City,Pingliang City,Gansu Province,Pingliang 744100,China)

机构地区：[1]甘肃省平凉市华亭市第一人民医院,甘肃平凉744100

出　　处：《心理月刊》2025年第6期154-156,共3页

摘　　要：目的探析对脑梗死后抑郁患者开展帕罗西汀和心理治疗的临床效果。方法纳入2023年1月~2023年12月在甘肃省平凉市华亭市第一人民医院进行治疗的病例,均符合脑梗死后抑郁病症,整理数据64例,采取双色球平均法将这些患者分为两组,每组均有32例。对照组采用帕罗西汀进行单一治疗,观察组则在对照组基础上联合心理治疗,对两组的心理健康、睡眠质量、焦虑情绪、抑郁情绪和神经功能进行对比。正态计量资料以t检验。结果干预后,观察组心理健康各项指标评分均较对照组低,睡眠质量、抑郁、焦虑评分较对照组低,观察组的Fugl-Meyer运动功能评估量表(FMAS)和Berg平衡量表(BBS)评分分值均比对照组高,而美国国立卫生研究院卒中量表(NHISS)评分低于对照组(P<0.05)。结论对脑梗死后抑郁患者开展帕罗西汀和心理治疗联合疗法,可有效改善患者的心理健康状态、睡眠质量、焦虑和抑郁情绪,提升其神经功能,改善患者的预后和生活质量。Objective To explore the clinical efficacy of paroxetine and psychological therapy in patients with post-stroke depression.Methods A total of 64 patients who received treatment at Huating First People's Hospital in Pingliang City,Gansu Province from January 2023 to December 2023 were included,all of whom were diagnosed with post-stroke depression.The data was collected and divided into two groups using the double color ball averaging method,with 32 patients in each group.The control group received single treatment with paroxetine,while the observation group received combined psychological therapy based on the control group.The mental health,sleep quality,anxiety,depression,and neurological function of the two groups were compared.Normal metrological data is tested using t-test.Results After the intervention,the scores of various indicators of mental health in the observation group were lower than those in the control group,and the scores of sleep quality,depression,and anxiety were lower than those in the control group.The scores of Fugl-Meyer assessment scale(FMAS)and Berg balance scale(BBS)in the observation group were higher than those in the control group,while the National Institute of Health stroke scale(NHISS)score in the United States was lower than that in the control group(P<0.05).Conclusion The combination therapy of paroxetine and psychotherapy for patients with post-stroke depression can effectively improve their mental health status,sleep quality,anxiety,and depressive emotions,enhance their neurological function,and improve their prognosis and quality of life.

关 键 词：脑梗死 帕罗西汀 心理治疗 抑郁 神经功能 

分 类 号：R47[医药卫生—护理学]